Folic acid cas no:59-30-3
Synonyms: 4-Pteridinol, 2-amino-6-((p-((1, 3-dicarboxypropyl)carbamoyl)anilino)methyl)-;Acido folico [INN-Spanish];Folsav;(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-7-yl)methylamino]benzoyl]amino]pentanedioate;Vitamin M;Pteroyl-L-monoglutamic acid;Folvite;Folaemin [Netherlands];L-Glutamic acid, N-(4-((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-;Folico (Italy);pteridinyl)methyl]amino]benzoyl]-;Kyselina listova [Czech];Folettes;Folipac;Foliamin;(2R)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioate;Folasic (Australia);Incafolic;L-Glutamic acid,N-[4-[[(2-amino-1,4- dihydro-4-oxo-6-pteridinyl)methyl]amino]- benzoyl]-;Glutamic acid, pteroyl-, L-;Folic acid (TN);L-glutamic acid, N-[4-[[(2-amino-4,8-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-;Vitamin Be;(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid;Pteroylmonoglutamate;Glutamic acid, N-[p-[[(2-amino-4-hydroxypyrimido(4, 5-b)pyrazin-6-yl)methyl]amino]benzoyl]-, L;L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, K salt;Folate;Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, L-;Folacin;Vitamin B9;
NameFolic acid
CAS59-30-3
Synonyms4-Pteridinol, 2-amino-6-((p-((1, 3-dicarboxypropyl)carbamoyl)anilino)methyl)-;Acido folico [INN-Spanish];Folsav;(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-7-yl)methylamino]benzoyl]amino]pentanedioate;Vitamin M;Pteroyl-L-monoglutamic acid;Folvite;Folaemin [Netherlands];L-Glutamic acid, N-(4-((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-;Folico (Italy);pteridinyl)methyl]amino]benzoyl]-;Kyselina listova [Czech];Folettes;Folipac;Foliamin;(2R)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioate;Folasic (Australia);Incafolic;L-Glutamic acid,N-[4-[[(2-amino-1,4- dihydro-4-oxo-6-pteridinyl)methyl]amino]- benzoyl]-;Glutamic acid, pteroyl-, L-;Folic acid (TN);L-glutamic acid, N-[4-[[(2-amino-4,8-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-;Vitamin Be;(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid;Pteroylmonoglutamate;Glutamic acid, N-[p-[[(2-amino-4-hydroxypyrimido(4, 5-b)pyrazin-6-yl)methyl]amino]benzoyl]-, L;L-Glutamic acid, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, K salt;Folate;Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-, L-;Folacin;Vitamin B9;
EINECS(EC#)200-419-0
Molecular FormulaC19H19N7O6
Molecular Weight441.4
AppearanceYellow to orange yellow crystals or crystalline powder.
alpha20° (C=1, 0.1N NAOH)
storage temp2-8°C
Hazard Xn
Risk R33;R62;R68
Safety
Risk Statements: 33-62-68
R33: Danger of cumulative effects.
R62: Risk of impaired fertility.
R68: Possible risk of irreversible effects.
Safety Statements: 24/25
S24/25: Avoid contact with skin and eyes.
WGK Germany: 1
RTECS: LP5425000
F: 8
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| guinea pig |
LD50 |
intravenous |
120mg/kg (120mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 1409, 1995. |
| mouse |
LD50 |
intraperitoneal |
85mg/kg (85mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: COMA |
Experientia. Vol. 41, Pg. 72, 1985. |
| mouse |
LD50 |
intravenous |
282mg/kg (282mg/kg) |
? |
Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. |
| mouse |
LD50 |
oral |
10gm/kg (10000mg/kg) |
|
Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. |
| mouse |
LDLo |
subcutaneous |
200mg/kg (200mg/kg) |
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
BLOOD: CHANGES IN SPLEEN |
Proceedings of the Society for Experimental Biology and Medicine. Vol. 71, Pg. 544, 1949. |
| rabbit |
LD50 |
intravenous |
410mg/kg (410mg/kg) |
|
Drugs in Japan Vol. -, Pg. 1409, 1995. |
| rat |
LD50 |
intravenous |
500mg/kg (500mg/kg) |
|
Drugs in Japan Vol. -, Pg. 1409, 1995. |
