Benzenemethanol,3-hydroxy-a-[(methylamino)methyl]-, (aR)- cas no:59-42-7
Synonyms: m-Methylaminoethanolphenol;m-Oxedrine;m-Sympathol;Benzenemethanol,3-hydroxy-a-[(methylamino)methyl]-, (R)-;Benzyl alcohol, m-hydroxy-a-[(methylamino)methyl]-, (-)- (7CI,8CI);(-)-Phenylephrine;(-)-m-Hydroxy-a-(methylaminomethyl)benzylalcohol;(-)-m-Oxedrine;(-)-m-Synephrine;(R)-(-)-Phenylephrine;(R)-Phenylephrine;L-Phenylephedrine;Mesaton;Mesatone;Metaoxedrin;Metaoxedrine;Metasympatol;Metasynephrine;Mezaton;Neo-Synephrine;Phenylephrine;R(-)-Mezaton;Visadron;l-m-Hydroxy-a-[(methylamino)methyl]benzylalcohol;m-Sympatol;m-Synephrine;
NameBenzenemethanol,3-hydroxy-a-[(methylamino)methyl]-, (aR)-
CAS59-42-7
Synonymsm-Methylaminoethanolphenol;m-Oxedrine;m-Sympathol;Benzenemethanol,3-hydroxy-a-[(methylamino)methyl]-, (R)-;Benzyl alcohol, m-hydroxy-a-[(methylamino)methyl]-, (-)- (7CI,8CI);(-)-Phenylephrine;(-)-m-Hydroxy-a-(methylaminomethyl)benzylalcohol;(-)-m-Oxedrine;(-)-m-Synephrine;(R)-(-)-Phenylephrine;(R)-Phenylephrine;L-Phenylephedrine;Mesaton;Mesatone;Metaoxedrin;Metaoxedrine;Metasympatol;Metasynephrine;Mezaton;Neo-Synephrine;Phenylephrine;R(-)-Mezaton;Visadron;l-m-Hydroxy-a-[(methylamino)methyl]benzylalcohol;m-Sympatol;m-Synephrine;
EINECS(EC#)200-424-8
Molecular FormulaC9H13NO2
Molecular Weight167.21
refractive index-55.5 ° (C=5, 1mol/L HCl)
Risk R22
Safety
Risk Statements: 22-36/37/38
R22: Harmful if swallowed
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36: Wear suitable protective clothing
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible)
RTECS: DO7175000
Hazardous Substances Data: 59-42-7(Hazardous Substances Data)
Poison by ingestion, subcutaneous, intravenous, intraperitoneal, and intraduodenal routes. Human systemic effects by ocular route: blood pressure increase. An experimental teratogen. Other experimental reproductive effects. A nasal decongestant. When heated to decomposition it emits toxic fumes of NOx.
| 1. |
|
ocu-wmn TDLo:188 µg/kg:CVS
|
|
ANESAV Anesthesiology. 36 (1972),187. |
| 2. |
|
ocu-inf TDLo:5500 µg/kg:CVS
|
|
ANESAV Anesthesiology. 36 (1972),187. |
| 3. |
|
orl-rat LD50:350 mg/kg
|
|
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 180 (1969),155. |
| 4. |
|
scu-rat LD50:28 mg/kg
|
|
JPETAB Journal of Pharmacology and Experimental Therapeutics. 85 (1945),119. |
| 5. |
|
ipr-mus LDLo:60 mg/kg
|
|
JPETAB Journal of Pharmacology and Experimental Therapeutics. 160 (1968),22. |
| 6. |
|
scu-mus LD50:875 mg/kg
|
|
FATOAO Farmakologiya i Toksikologiya (Moscow). 28 (1965),46. |
| 7. |
|
ivn-mus LD50:38 mg/kg
|
|
APTOA6 Acta Pharmacologica et Toxicologica. 38 (1976),474. |
