4-Chloro-3-methylphenol cas no:59-50-7
Synonyms: 6-Chloro-3-hydroxytoluene; 2-Chloro-5-hydroxytoluene; 3-Methyl-4-chlorophenol; p-Chloro-m-cresol; 4-Chloro-m-cresol; 4-Chloro-m-cresol; PCMC; 4-Chloro-m-cresol (OH=1); 4-Chloro-m-cresol 98+ %; 4-Chloro-l,3-Methylphenol
Name4-Chloro-3-methylphenol
CAS59-50-7
Synonyms6-Chloro-3-hydroxytoluene; 2-Chloro-5-hydroxytoluene; 3-Methyl-4-chlorophenol; p-Chloro-m-cresol; 4-Chloro-m-cresol; 4-Chloro-m-cresol; PCMC; 4-Chloro-m-cresol (OH=1); 4-Chloro-m-cresol 98+ %; 4-Chloro-l,3-Methylphenol
EINECS(EC#)200-431-6
Molecular FormulaC7H7ClO
Molecular Weight142.58
AppearanceOff white crystals
refractive index1.5403 (73 C)
storage tempStore in a cool, dry place. Keep container closed when not in use.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Hazard Xn:Harmful
Risk R21/22;R41;R43;R50
Safety
Hazard Codes of 4-Chloro-3-methylphenol (CAS NO.59-50-7):?Xn,N,T,F
Risk Statements: 21/22-41-43-50-39-23/24/25-11-38?
R21/22: Harmful in contact with skin and if swallowed.?
R41: Risk of serious damage to the eyes.?
R43: May cause sensitization by skin contact.?
R50: Very toxic to aquatic organisms.?
R39: Danger of very serious irreversible effects.?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.?
R11: Highly flammable.?
R38: Irritating to skin.
Safety Statements: 26-36/37/39-61-45-16-7-28?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S16: Keep away from sources of ignition.?
S7: Keep container tightly closed.?
S28: After contact with skin, wash immediately with plenty of soap-suds.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: GO7100000
HazardClass: 6.1(a)
PackingGroup: II
HS Code: 29081000
Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. An allergen. Mutation data reported. Incompatible with sodium hydroxide. When heated to decomposition it emits toxic fumes of Cl? and phosgene. See also CRESOL and CHLOROPHENOLS.
HS Code 29081000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intravenous |
70mg/kg (70mg/kg) |
BEHAVIORAL: COMA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 212, 1939. |
| mouse |
LD50 |
oral |
600mg/kg (600mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989. |
| mouse |
LD50 |
subcutaneous |
360mg/kg (360mg/kg) |
BEHAVIORAL: GENERAL ANESTHETIC
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 212, 1939. |
| rat |
LD50 |
oral |
1830mg/kg (1830mg/kg) |
? |
Personal Communication from P. Schmitz, Bayer AG, 5090 Leverkusen, Bayerwerk, Fed. Rep. Ger., April 4, 1986Vol. 04APR1986, |
| rat |
LD50 |
subcutaneous |
400mg/kg (400mg/kg) |
? |
Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 212, 1939. |
