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2,3-Dimercapto-1-propanol cas no:59-52-9

Synonyms: Dimercaprol; 2,3-Dimercaptopropanol; BAL

Identification
Name2,3-Dimercapto-1-propanol
CAS59-52-9
SynonymsDimercaprol; 2,3-Dimercaptopropanol; BAL
EINECS(EC#)200-433-7
Molecular FormulaC3H8OS2
Molecular Weight124.22
Chemical Properties
Appearanceclear almost colorless liquid.
refractive index1.57-1.574
storage temp2-8°C
Sensitive Air Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard Xi:Irritant;
Risk R22;R36/38
Safety

Poison via ingestion, intramuscular, parenteral, intraperitoneal, and intravenous routes. Experimental teratogenic effects. Human systemic effects by intramuscular route: hemorrhage and dermatitis. Human blood and systemic skin effects by intramuscular route. It causes redness and swelling when applied locally to the skin, but does not produce blisters or ulcers. Intensely irritating to eyes and mucous membranes. Systemic symptoms are caused by injection. When heated to decomposition, it emits toxic fumes of SOx. Used as an antidote to arsenic, gold, and mercury poisoning.

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-36/38 
R22:Harmful if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R36/38:Irritating to eyes and skin.
Safety Statements: 26-36-24/25-23 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
S24/25:Avoid contact with skin and eyes. 
S23:Do not breathe vapour.
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
F: 8-9-13-23
HazardClass: 6.1
PackingGroup: III
RTECS: UB2625000


HS Code 29309070

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo intramuscular 3mg/kg (3mg/kg) BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Science. Vol. 102, Pg. 601, 1945.
mouse LD50 intramuscular 113mg/kg (113mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 223, Pg. 408, 1954.
mouse LD50 intraperitoneal 25mg/kg (25mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 intravenous 56mg/kg (56mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04985,
mouse LD50 oral 217mg/kg (217mg/kg)   Quarterly Journal of Pharmacy & Pharmacology. Vol. 21, Pg. 364, 1948.
mouse LD50 unreported 99mg/kg (99mg/kg)   Fukuoka Igaku Zasshi. Vol. 49, Pg. 2779, 1958.
rabbit LD50 intramuscular 50mg/kg (50mg/kg)   Biochemical Journal. Vol. 41, Pg. 325, 1947.
rabbit LD50 intravenous 50mg/kg (50mg/kg)   Biochemical Journal. Vol. 41, Pg. 325, 1947.
rabbit LD50 parenteral 40mg/kg (40mg/kg) VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION

VASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTION
Annales Pharmaceutiques Francaises. Vol. 5, Pg. 172, 1947.
rabbit LD50 unreported 80mg/kg (80mg/kg)   Fukuoka Igaku Zasshi. Vol. 49, Pg. 2779, 1958.
rat LD50 intramuscular 87mg/kg (87mg/kg)   Toxicology and Applied Pharmacology. Vol. 36, Pg. 297, 1976.
rat LD50 intraperitoneal 105mg/kg (105mg/kg)   Annales Pharmaceutiques Francaises. Vol. 5, Pg. 172, 1947.
rat LD50 subcutaneous 2gm/kg (2000mg/kg)   Annales Pharmaceutiques Francaises. Vol. 5, Pg. 172, 1947.
rat LD50 unreported 113mg/kg (113mg/kg)   Fukuoka Igaku Zasshi. Vol. 49, Pg. 2779, 1958.

supplier list

Tianjin Harmony Technology Development Co., Ltd.
Tel:
Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
Wuhan Grand Pharmaceutical Group Co., Ltd.
Tel:
Address: No. 5, Gutian Road, Wuhan Hubei China
Huzhou City Linghu Xinwang Chemical Co.,Ltd.
Tel:86-572-3948695 3943638 3948615 3948612
Address: Linghu Develop Zone Huzhou Zhejiang,China
NORBRIGHT INDUTRY CO., LTD
Tel:
Address: E7602+03, BINHAI JINRONGJIE, 20 GUANGCHANGDONG ROAD,TEDA, TIANJIN 300457 CHINA
HBCChem, Inc.
Tel:+1-510-219-6317
Address:
Parish Chemical Company
Tel:+1-(801)-226-2018
Address: P.O Box 277, Orem, Utah 84059-0277,
Sciencelab.com, Inc.
Tel:+1-(281)-441-4400
Address: 14025, Smith Road, Houston, Texas 77396,
Tripletoxygen
Tel:
Address: P.O. Box 20650, Houston, Texas 77225,
Taizhou P&J International Trade Co., Ltd.
Tel:+86-(576)-86137488, 86137955
Address: 901 Room, Xingyuan Mansion, Wenling, Zhejiang 317500,
Shanghai Wenshui Chemical Co., Ltd.
Tel:+86-(21)-6631-2210, 6631-2209
Address: No. 301 C-207, Wenshui,
ADVANCED TECH. & IND. CO., LTD.
Tel:86-23902293
Address: UNIT B, 1/F, CHEONG SHING IND. BLDG., 17 WALNUT ST., TAI KOK TSUI, KLN, HONG KONG
Applichem GmbH
Tel:+49-(6151)-93570
Address: 4, Ottoweg, Darmstadt 64291,
lotuschem
Tel:852-29738324
Address: Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong
HangZhou Peak Chemical Co.,Ltd
Tel:+86-571-88233073
Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China
YiPeng Chemical
Tel:571 85376369
Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China

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