59-67-6|Nicotinic acidProducts Supply - Chemical intermediates Network

Nicotinic acid cas no:59-67-6

Synonyms: Nicocidin;Efacin;Nicocap;Niacor;Niac;Nicamin;Nicotinipca;Daskil;Nicotene;Nicosan 3;Nicodon;Nicobid;Davitamon PP;pyridine-3-carboxylate;NICO;Peviton;Nicovasan;Nicotamin;Pellagrin;Niconat;Enduracin;Nicangin;Nicodelmine;Niacin (vitamin B3);Nicotinic acid(Medicine used);Nikotinsaeure;Niacin;

Identification

NameNicotinic acid
CAS59-67-6
SynonymsNicocidin;Efacin;Nicocap;Niacor;Niac;Nicamin;Nicotinipca;Daskil;Nicotene;Nicosan 3;Nicodon;Nicobid;Davitamon PP;pyridine-3-carboxylate;NICO;Peviton;Nicovasan;Nicotamin;Pellagrin;Niconat;Enduracin;Nicangin;Nicodelmine;Niacin (vitamin B3);Nicotinic acid(Medicine used);Nikotinsaeure;Niacin;
EINECS(EC#)200-441-0
Molecular FormulaC₆H₅NO₂
Molecular Weight123.11

Chemical Properties

AppearanceWhite crystalline powder
refractive index1.4936
storage temp0-6°C

Safety Data

Hazard Xi:;
Risk R36/37/38
Safety

Poison by intraperitoneal route. Moderately toxic by ingestion, intravenous, and subcutaneous routes. Human systemic effects: change in clotting factors, changes in platelet count. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:?Xi
Risk Statements: 36/37/38?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-24/25?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36: Wear suitable protective clothing.?
S24/25: Avoid contact with skin and eyes.
WGK Germany of Niacin (CAS NO.59-67-6): 1

HS Code 29362990

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	intravenous	3500mg/kg (3500mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Proceedings of the Society for Experimental Biology and Medicine. Vol. 38, Pg. 241, 1938.
man	TDLo	intravenous	357ug/kg (0.357mg/kg)	CARDIAC: CARDIAC OUTPUT LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Annals of Internal Medicine. Vol. 29, Pg. 558, 1948.
man	TDLo	oral	2571mg/kg/90D (2571mg/kg)	BLOOD: CHANGE IN CLOTTING FACTORS BLOOD: CHANGES IN PLATELET COUNT	Archives of Internal Medicine. Vol. 152, Pg. 861, 1992.
man	TDLo	oral	9713mg/kg/58W (9713mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING SKIN AND APPENDAGES (SKIN): SWEATING: OTHER	Southern Medical Journal. Vol. 84, Pg. 496, 1991.
man	TDLo	oral	31200mg/kg/78 (31200mg/kg)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE	JAMA, Journal of the American Medical Association. Vol. 279, Pg. 1702, 1998.
mouse	LD50	intraperitoneal	358mg/kg (358mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 741, 1977.
mouse	LD50	intravenous	5gm/kg (5000mg/kg)	?	Therapie. Vol. 26, Pg. 831, 1971.
mouse	LD50	oral	3720mg/kg (3720mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 149, 1973.
mouse	LD50	subcutaneous	3500mg/kg (3500mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 741, 1977.
mouse	LD50	unreported	4gm/kg (4000mg/kg)	?	British UK Patent Application. Vol. #2041937,
rabbit	LD50	oral	4550mg/kg (4550mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 741, 1977.
rat	LD50	intraperitoneal	730mg/kg (730mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 741, 1977.
rat	LD50	oral	7gm/kg (7000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 544, 1982.
rat	LD50	subcutaneous	5gm/kg (5000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 544, 1982.
rat	LD50	unreported	4gm/kg (4000mg/kg)	?	United States Patent Document. Vol. #4412998,
rat	LDLo	intravenous	3500mg/kg (3500mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Proceedings of the Society for Experimental Biology and Medicine. Vol. 38, Pg. 241, 1938.

supplier list

AerChem and Xena International LLC: Tel:812-334-9996; Address: P.O. Box 177

Ceresking Ecology & Technology Co.,Ltd.: Tel:86-22-66218397; Address: 2-505, Guoxin Bldg A, The 2ND Street, TEDA, Tianjin, China

Gurvey & Berry Co. Inc.: Tel:+1-416-2595700; Address: 310 Judson Street, Unit #15,Toronto, Ontario Canada

Qingdao Chinaoil Co., Ltd: Tel:; Address: 22/F,Golden Light Tower,No.56, Xianggang Zhong Road, Qingdao 266071, China

Shanghai Experiment Reagent Co.,LTD.: Tel:0086-21-56558317 56553837; Address: 10-603, No.555 Luding Road (No.1000 North Zhongshan Road),Shanghai

PhytoTechnology Laboratories: Tel:+1-913-3415343; Address: PhytoTechnology Laboratories,P.O. Box 13481,Shawnee Mission, KS

TECHNO PHRAMCHEM: Tel:+91-11-27112184, 27226915; Address: 101-A, Deep Enclave, Pocket - D, Ashok Vihar, Phase - III, Delhi - 110052 (INDIA)

Ralston Colour Systems: Tel:+31.38.4291100; Address: P.O. Box 205 NL-8000 AE Zwolle The Netherlands

DNP International Co., Inc.: Tel:+1-562-692-8945; Address: 3035 Red Hat Lane, Whittier, CA 90601

Major Chemicals Co.,Ltd.: Tel:; Address: Rm.3A05,Sunshine International Commercial Center,No.186-1,Hushu South Road,Hangzhou,the P.R.of China

Jiaxing Easydo (Chino Holdings) Limited: Tel:; Address:

ANF INNOVATIONS PTY LTD: Tel:+61 2 8003 3175; Address: PO Box 420, Spit Junction,NSW, 2088,Australia

SINOCO CHEMICAL CO., LIMITED: Tel:+86-571-81956191, 81956192; Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.

Shanghai Entropy Chemical Co., Ltd.: Tel:+86-(21)-5512-2488; Address: Fengxian District, Shanghai 201400,

Hangzhou Shengda Pharmaceutical Co., Ltd.: Tel:+86-(571)-6355-7568; Address:

Nicotinic acid cas no:59-67-6

Directory

supplier list