L-DOPA cas no:59-92-7
Synonyms: L-3-(3,4-Dihydroxyphenyl)alanine; Levodopa; L-DOPA 3,4-L-Dihydroxyphenylalanine; 3-Hydroxy-L-tyrosine; H-Tyr(3-OH)-OH; L-3-Hydroxytyrosine
NameL-DOPA
CAS59-92-7
SynonymsL-3-(3,4-Dihydroxyphenyl)alanine; Levodopa; L-DOPA 3,4-L-Dihydroxyphenylalanine; 3-Hydroxy-L-tyrosine; H-Tyr(3-OH)-OH; L-3-Hydroxytyrosine
EINECS(EC#)200-445-2
Molecular FormulaC9H11NO4
Molecular Weight197.19
AppearanceColorless Crystalline Powder
alpha-11.7 o (C=5.3, 1N HCL)
refractive index-12 ° (C=5, 1mol/L HCl)
storage temp2-8°C
Hazard Xn:Harmful
Risk R22
Safety
Poison by ingestion. Moderately toxic by intravenous and intraperitoneal routes. Human systemic effects by ingestion: somnolence, hallucinations and distorted perceptions, toxic psychosis, motor activity changes, ataxia, dyspnea. Experimental teratogenic and reproductive effects. Questionable human carcinogen producing skin tumors. Human mutation data reported. An anticholinergic agent used as an anti-Parkinsonian drug. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:? Xi
The Risk Statements information of? D-glucose?:
41:? Risk of serious damage to eyes?
36/37/38:? Irritating to eyes, respiratory system and skin?
The Risk Statements information of? D-glucose?:
22:? Do not breathe dust?
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing
24/25:? Avoid contact with skin and eyes??
WGK Germany: 1
Hazard Note: Irritant/Light Sensitive
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dnr-bcs 500?μg/disc
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MUREAV ?? Mutation Research. 137 (1984),17. |
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dni-hmn:fbr 3?mmol/L
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CNREA8 ?? Cancer Research. 42 (1982),3783. |
| 3. |
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orl-man TDLo:87,520?mg/kg/1.5Y-C:CAR,SKN
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NEURAI ?? Neurology. 24 (1974),340. |
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orl-wmn TDLo:320?mg/kg/4D-I
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AHJOA2 ?? American Heart Journal. 110 (1985),488. |
| 5. |
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orl-hmn TDLo:156?g/kg/10Y:CNS
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JNNPAU ?? Journal of Neurology, Neurosurgery and Psychiatry. 34 (1971),502. |
| 6. |
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orl-hmn TDLo:13?g/kg/1Y:CNS,PUL
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JNNPAU ?? Journal of Neurology, Neurosurgery and Psychiatry. 34 (1971),668. |
| 7. |
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orl-rat LD50:1780?mg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 28 (1974),1. |
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ipr-rat LD50:624?mg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 28 (1974),1. |
| 9. |
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orl-mus LD50:2363?mg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 28 (1974),1. |
| 10. |
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ipr-mus LD50:588?mg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 28 (1974),1. |
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?Levodopa (CAS NO.59-92-7) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
