1H-Imidazole,4,5-dihydro-2-(phenylmethyl)- cas no:59-98-3

Name1H-Imidazole,4,5-dihydro-2-(phenylmethyl)-
CAS59-98-3
Synonyms2-Imidazoline,2-benzyl- (8CI); Imidazoline, 2-benzyl- (6CI); 2-Benzyl-2-imidazoline;2-Benzyl-4,5-dihydro-1H-imidazole; 2-Benzyl-4,5-imidazoline;2-Benzylimidazoline; Artonil; Benzazoline; Benzidazol; Benzolin; Benzolin(vasodilator); Benzylimidazoline; Dilatol ASI; Divascol; Imidalin; Imidaline;Kasimid; Lambril; NSC 35110; Olitensol; Peripherine; Phenylmethylimidazoline;Prefaxil; Priscol; Priscoline; Tolazolin; Tolazoline; Vasimid; Vasodil
EINECS(EC#)200-448-9
Molecular FormulaC10H12 N2
Molecular Weight160.24

Hazard Xn: Harmful;
Risk R20/21/22;R36/37/38
Safety Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

NJ1925000

CHEMICAL NAME :

2-Imidazoline, 2-benzyl-

CAS REGISTRY NUMBER :

59-98-3

BEILSTEIN REFERENCE NO. :

0128757

LAST UPDATED :

199710

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C10-H12-N2

MOLECULAR WEIGHT :

160.24

WISWESSER LINE NOTATION :

T5M CN BUTJ B1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

350 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

160 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

40 mg/kg

TOXIC EFFECTS :

Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

50 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - hamster Lung

DOSE/DURATION :

62500 ug/L

REFERENCE :

GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981