1-Propanaminium,2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (1:1) cas no:590-63-6
Synonyms: (2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI);1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (9CI);Ammonium, (2-hydroxypropyl)trimethyl-, chloride, carbamate(8CI);Besacholine;Bethanechol chloride;Carbamylmethylcholine chloride;Mechotane;Mechothane;Mecothane;Mictone;Myocholine;Myotonachol;Myotonine chloride;NSC 30783;Trimethyl(2-carbamoyloxypropyl)ammonium chloride;Urecholine;Urecholinechloride;Uro-Carb;b-Methyl carbachol chloride;b-Methylcholine chloride urethan;
Name1-Propanaminium,2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (1:1)
CAS590-63-6
Synonyms(2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI);1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (9CI);Ammonium, (2-hydroxypropyl)trimethyl-, chloride, carbamate(8CI);Besacholine;Bethanechol chloride;Carbamylmethylcholine chloride;Mechotane;Mechothane;Mecothane;Mictone;Myocholine;Myotonachol;Myotonine chloride;NSC 30783;Trimethyl(2-carbamoyloxypropyl)ammonium chloride;Urecholine;Urecholinechloride;Uro-Carb;b-Methyl carbachol chloride;b-Methylcholine chloride urethan;
EINECS(EC#)209-686-8
Molecular FormulaC7H17N2O2.Cl
Molecular Weight196.68
Appearancewhite crystalline
storage temp2-8°C
Hazard Xn
Risk R22
Safety
Poison by ingestion, subcutaneous, intramuscular and intravenous routes. Human systemic effects by subcutaneous route: allergic dermatitis and sweating. Used as a synthetic cholinergic drug. When heated to decomposition it emits very toxic fumes of NH3, NOx, and Cl?. See also CARBAMATES.
Hazard Codes:
Xn: Harmful .gif)
Risk Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
R22 Harmful if swallowed.
Safety Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
| 1. |
??? |
scu-hmn TDLo:130?mg/kg:SKN
|
??? |
34ZIAG ?? Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.:?Academic Press, Inc.,1969,130. |
| 2. |
??? |
scu-man TDLo:1071?μg/kg/3D-I:SKN
|
??? |
ARDEAC ?? Archives of Dermatology. 95 (1967),499. |
| 3. |
??? |
orl-rat LD50:1500?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. |
| 4. |
??? |
scu-rat LD50:175?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. |
| 5. |
??? |
ivn-rat LD50:21?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. |
| 6. |
??? |
ims-rat LD50:220?mg/kg
|
??? |
NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),139. |
| 7. |
??? |
orl-mus LD50:250?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. |
| 8. |
??? |
scu-mus LD50:120?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. |
| 9. |
??? |
ivn-mus LD50:10?mg/kg
|
??? |
JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337. |
| 10. |
??? |
ims-mus LD50:192?
|
