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1-Propanaminium,2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (1:1) cas no:590-63-6

Synonyms: (2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI);1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (9CI);Ammonium, (2-hydroxypropyl)trimethyl-, chloride, carbamate(8CI);Besacholine;Bethanechol chloride;Carbamylmethylcholine chloride;Mechotane;Mechothane;Mecothane;Mictone;Myocholine;Myotonachol;Myotonine chloride;NSC 30783;Trimethyl(2-carbamoyloxypropyl)ammonium chloride;Urecholine;Urecholinechloride;Uro-Carb;b-Methyl carbachol chloride;b-Methylcholine chloride urethan;

Identification
Name1-Propanaminium,2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (1:1)
CAS590-63-6
Synonyms(2-Hydroxypropyl)trimethylammoniumchloride carbamate (6CI);1-Propanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-,chloride (9CI);Ammonium, (2-hydroxypropyl)trimethyl-, chloride, carbamate(8CI);Besacholine;Bethanechol chloride;Carbamylmethylcholine chloride;Mechotane;Mechothane;Mecothane;Mictone;Myocholine;Myotonachol;Myotonine chloride;NSC 30783;Trimethyl(2-carbamoyloxypropyl)ammonium chloride;Urecholine;Urecholinechloride;Uro-Carb;b-Methyl carbachol chloride;b-Methylcholine chloride urethan;
EINECS(EC#)209-686-8
Molecular FormulaC7H17N2O2.Cl
Molecular Weight196.68
Chemical Properties
Appearancewhite crystalline
storage temp2-8°C
Safety Data

Hazard Xn
Risk R22
Safety

Poison by ingestion, subcutaneous, intramuscular and intravenous routes. Human systemic effects by subcutaneous route: allergic dermatitis and sweating. Used as a synthetic cholinergic drug. When heated to decomposition it emits very toxic fumes of NH3, NOx, and Cl?. See also CARBAMATES.
Hazard Codes:
Xn: Harmful
Risk Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
R22 Harmful if swallowed.
Safety Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.


Toxicity
1. ???

scu-hmn TDLo:130?mg/kg:SKN

??? 34ZIAG ?? Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.:?Academic Press, Inc.,1969,130.
2. ???

scu-man TDLo:1071?μg/kg/3D-I:SKN

??? ARDEAC ?? Archives of Dermatology. 95 (1967),499.
3. ???

orl-rat LD50:1500?mg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
4. ???

scu-rat LD50:175?mg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
5. ???

ivn-rat LD50:21?mg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
6. ???

ims-rat LD50:220?mg/kg

??? NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),139.
7. ???

orl-mus LD50:250?mg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
8. ???

scu-mus LD50:120?mg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
9. ???

ivn-mus LD50:10?mg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
10. ???

ims-mus LD50:192?

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Farchemia S.r.l.
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Chemner Pharma
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ACIC Fine Chemicals Inc.
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Trust & We Co., Ltd.
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AOKChem Co., Ltd.
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Hangzhou Sage Chemical Co., Ltd.
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Shanghai Xunxin Chemical Co., Ltd
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Watson International Ltd.
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Laiwu Hehui Chemical Co.,Ltd.
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China Langchem Inc.
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Kouting Chemical Co.,Ltd
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Atul Ltd
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lotuschem
Tel:852-29738324
Address: Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong
HangZhou Peak Chemical Co.,Ltd
Tel:+86-571-88233073
Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China

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