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Misoprostol cas no:59122-46-2

Synonyms: Cytotec;Isprelor;Misogon;Misoprost;Misoprostil;SC 29333;

Identification
NameMisoprostol
CAS59122-46-2
SynonymsCytotec;Isprelor;Misogon;Misoprost;Misoprostil;SC 29333;
Molecular FormulaC22H38O5
Molecular Weight382.53412
Chemical Properties
Appearancewater-soluble, viscous liquid
storage temp−20°C
Safety Data

Hazard T: Toxic;
Risk R60;R61;R25
Safety

Hazard Codes of Misoprostol (CAS NO.59122-46-2): ToxicT
Risk Statements: 45-60-61-25-36/37/38 
R45: May cause cancer. 
R60: May impair fertility. 
R61: May cause harm to the unborn child. 
R25: Toxic if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 53-22-36/37/39-45 
S53: Avoid exposure - obtain special instructions before use. 
S22: Do not breathe dust. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 2
RTECS: UK8390000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 10mg/kg (10mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 35, Pg. 1055, 1993.
mouse LD50 intramuscular 16mg/kg (16mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 33, 1985.
mouse LD50 intraperitoneal 70mg/kg (70mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Digestive Diseases and Sciences. Vol. 30, Pg. 142S, 1985.
mouse LD50 oral 27mg/kg (27mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Digestive Diseases and Sciences. Vol. 30, Pg. 142S, 1985.
rat LD50 intramuscular 19mg/kg (19mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 33, 1985.
rat LD50 intraperitoneal 40mg/kg (40mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Digestive Diseases and Sciences. Vol. 30, Pg. 142S, 1985.
rat LD50 oral 81mg/kg (81mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 33, 1985.

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