59122-46-2|MisoprostolProducts Supply - Chemical intermediates Network

Misoprostol cas no:59122-46-2

Synonyms: Cytotec;Isprelor;Misogon;Misoprost;Misoprostil;SC 29333;

Identification

NameMisoprostol
CAS59122-46-2
SynonymsCytotec;Isprelor;Misogon;Misoprost;Misoprostil;SC 29333;
Molecular FormulaC₂₂H₃₈O₅
Molecular Weight382.53412

Chemical Properties

Appearancewater-soluble, viscous liquid
storage temp−20°C

Safety Data

Hazard T: Toxic;
Risk R60;R61;R25
Safety

Hazard Codes of Misoprostol (CAS NO.59122-46-2): Toxic T
Risk Statements: 45-60-61-25-36/37/38
R45: May cause cancer.
R60: May impair fertility.
R61: May cause harm to the unborn child.
R25: Toxic if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 53-22-36/37/39-45
S53: Avoid exposure - obtain special instructions before use.
S22: Do not breathe dust.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 2
RTECS: UK8390000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	oral	10mg/kg (10mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 35, Pg. 1055, 1993.
mouse	LD50	intramuscular	16mg/kg (16mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 33, 1985.
mouse	LD50	intraperitoneal	70mg/kg (70mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Digestive Diseases and Sciences. Vol. 30, Pg. 142S, 1985.
mouse	LD50	oral	27mg/kg (27mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Digestive Diseases and Sciences. Vol. 30, Pg. 142S, 1985.
rat	LD50	intramuscular	19mg/kg (19mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 33, 1985.
rat	LD50	intraperitoneal	40mg/kg (40mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Digestive Diseases and Sciences. Vol. 30, Pg. 142S, 1985.
rat	LD50	oral	81mg/kg (81mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 11, Pg. 33, 1985.

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Misoprostol cas no:59122-46-2

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