PROXIL cas no:59209-40-4

NamePROXIL
CAS59209-40-4
SynonymsProglumetacin dimaleate;Protacine;Afloxan;CR-604;Proglumetacin maleate;Proglumetacina [Spanish];(1)-2-(4-(3-((4-Benzamido-5-(dipropylamino)glutaryl)oxy)propyl)-1-piperazinyl)ethyl 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate, compound with maleic acid (1:2);1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-2-(4-(3-((4-(benzoylamino)-5-(dipropylamino)-1,5-dioxopentyl)oxy)propyl)-1-piperazinyl)ethyl ester (+-)-, (Z)-2-butenedioate (1:2);3'-(4-(2-(1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-ylacetoxy)ethyl)piperazin-1-yl)propyl-4-benzamido-N,N-dipropylglutaramate (+-) dimaleate
EINECS(EC#)261-656-3
Molecular FormulaC46H58ClN5O8 . 2C4H4O4
Molecular Weight960.516

Safety

Poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl⁻ and NO_x. An anti-inflammatory agent.

1.		orl-rat LD50:170 mg/kg		OYYAA2    Oyo Yakuri. Pharmacometrics. 32 (1986),1173.
2.		ipr-rat LD50:247 mg/kg		OYYAA2    Oyo Yakuri. Pharmacometrics. 32 (1986),1173.
3.		scu-rat LD50:332 mg/kg		OYYAA2    Oyo Yakuri. Pharmacometrics. 32 (1986),1173.
4.		orl-mus LD50:67 mg/kg		OYYAA2    Oyo Yakuri. Pharmacometrics. 32 (1986),1173.
5.		ipr-mus LD50:243 mg/kg		OYYAA2    Oyo Yakuri. Pharmacometrics. 32 (1986),1173.