| child |
TDLo |
oral |
3gm/kg/22W-I (3000mg/kg) |
BLOOD: AGRANULOCYTOSIS
BLOOD: THROMBOCYTOPENIA |
American Journal of Emergency Medicine. Vol. 16, Pg. 396, 1998. |
| mammal (species unspecified) |
LD50 |
intravenous |
400mg/kg (400mg/kg) |
? |
Pharmacy International. Vol. 5, Pg. 191, 1984. |
| man |
TDLo |
intravenous |
134ug/kg/1D-I (0.134mg/kg) |
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" |
Lancet. Vol. 2, Pg. 385, 1985. |
| man |
TDLo |
intravenous |
107mg/kg/4D-I (107mg/kg) |
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" |
American Journal of Kidney Diseases. Vol. 22, Pg. 611, 1993. |
| man |
TDLo |
oral |
486mg/kg/17D- (486mg/kg) |
GASTROINTESTINAL: DECREASED MOTILITY OR CONSTIPATION
GASTROINTESTINAL: OTHER CHANGES |
American Journal of Gastroenterology. Vol. 88, Pg. 2110, 1993. |
| mouse |
LD50 |
intraperitoneal |
724mg/kg (724mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 25, Pg. 815, 1994. |
| mouse |
LD50 |
intravenous |
1118mg/kg (1118mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 866, 1985. |
| mouse |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
? |
Nature. Vol. 272, Pg. 583, 1978. |
| mouse |
LD50 |
subcutaneous |
1118mg/kg (1118mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 866, 1985. |
| rat |
LD50 |
intraperitoneal |
860mg/kg (860mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 866, 1985. |
| rat |
LD50 |
intravenous |
750mg/kg (750mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 25, Pg. 815, 1994. |
| rat |
LD50 |
oral |
> 20gm/kg (20000mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 7, 1990. |
| rat |
LD50 |
subcutaneous |
620mg/kg (620mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 866, 1985. |
| women |
LDLo |
multiple routes |
36mg/kg/2D-I (36mg/kg) |
BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES
BEHAVIORAL: COMA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
American Journal of Kidney Diseases. Vol. 20, Pg. 647, 1992. |
| women |
TDLo |
intravenous |
101mg/kg/2D-I (101mg/kg) |
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) |
American Journal of Medicine. Vol. 94, Pg. 212, 1993. |
| women |
TDLo |
oral |
12mg/kg/1D-I (12mg/kg) |
BRAIN AND COVERINGS: MENINGEAL CHANGES
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ANTIPSYCHOTIC |
Southern Medical Journal. Vol. 87, Pg. 1227, 1994. |
| women |
TDLo |
oral |
28mg/kg/2D-I (28mg/kg) |
BRAIN AND COVERINGS: CHANGES IN SURFACE EEG
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
LUNGS, THORAX, OR RESPIRATION: SPUTUM |
Southern Medical Journal. Vol. 87, Pg. 1227, 1994. |
| women |
TDLo |
oral |
80mg/kg/4D-I (80mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" |
Annals of Internal Medicine. Vol. 111, Pg. 187, 1989. |
| women |
TDLo |
oral |
100mg/kg/5D-I (100mg/kg) |
SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" |
British Medical Journal. Vol. 289, Pg. 1424, 1984. |
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