Bismuthine, trimethyl-(6CI,7CI,8CI,9CI) cas no:593-91-9

NameBismuthine, trimethyl-(6CI,7CI,8CI,9CI)
CAS593-91-9
SynonymsTrimethylbismuth;Trimethylbismuthine
EINECS(EC#)209-817-9
Molecular FormulaC3H9 Bi
Molecular Weight254.06

Safety

Poison by ingestion, inhalation, skin contact, intravenous, and subcutaneous routes. Can cause narcosis and central nervous system depression. Prolonged exposure can cause encephalopathy similar to that of organic lead compounds. Flammable when exposed to heat or flame; can react with oxidizing materials. Spontaneously flammable in air. Explodes at 110°C. Upon decomposition it emits toxic fumes of Bi. See also BISMUTH COMPOUNDS.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LCLo	inhalation	233mg/kg (233mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT BEHAVIORAL: MUSCLE WEAKNESS	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
dog	LD50	intravenous	12mg/kg (12mg/kg)	GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
dog	LD50	subcutaneous	182mg/kg (182mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
dog	LDLo	oral	233mg/kg (233mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
dog	LDLo	skin	233mg/kg (233mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
pigeon	LDLo	intravenous	6mg/kg (6mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD VASCULAR: SHOCK GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
rabbit	LD50	oral	484mg/kg (484mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
rabbit	LD50	subcutaneous	182mg/kg (182mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.
rabbit	LDLo	intravenous	11mg/kg (11mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 17, 1939.