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Home > products > 1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,hydrochloride (1:1), (3S)-

1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,hydrochloride (1:1), (3S)- cas no:5936-28-7

Synonyms: 1(3H)-Isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-,hydrochloride, [S-(R*,S*)]-; 1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,hydrochloride, (3S)- (9CI); Hydrastine, hydrochloride (8CI);1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv.; (1R,9S)-b-Hydrastine hydrochloride; b-Hydrastine hydrochloride

Identification
Name1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,hydrochloride (1:1), (3S)-
CAS5936-28-7
Synonyms1(3H)-Isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-,hydrochloride, [S-(R*,S*)]-; 1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,hydrochloride, (3S)- (9CI); Hydrastine, hydrochloride (8CI);1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv.; (1R,9S)-b-Hydrastine hydrochloride; b-Hydrastine hydrochloride
EINECS(EC#)227-692-9
Molecular FormulaC21H21 N O6 . Cl H
Molecular Weight419.89
Chemical Properties
storage temp−20°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn
Risk 22
Safety

Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Safety Information of Hydrastine hydrochloride (CAS NO.5936-28-7):
Hazard Codes: XnHarmful
Risk Statements: 22 
22:  Harmful if swallowed
Safety Statements: 36
36:  Wear suitable protective clothing
RIDADR: 1544
RTECS: MU6125000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 1gm/kg (1000mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 57, 1969.
rat LD50 subcutaneous 1270mg/kg (1270mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 57, 1969.

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