59703-84-3|Piperacillin sodium saltProducts Supply

Piperacillin sodium salt cas no:59703-84-3

Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, [2S-[2a,5a,6b(S*)]]-;Piperacillin sodium;Piperacillin-Na;Sodium piperacillin;

Identification

NamePiperacillin sodium salt
CAS59703-84-3
Synonyms4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, [2S-[2a,5a,6b(S*)]]-;Piperacillin sodium;Piperacillin-Na;Sodium piperacillin;
EINECS(EC#)261-868-6
Molecular FormulaC₂₃H₂₆N₅NaO₇S
Molecular Weight517.55478

Chemical Properties

AppearanceWhite to off-white crystalline powder
refractive index180 ° (C=0.8, H2O)
storage tempStore at 0-5°C

Safety Data

Hazard Xn:Harmful
Risk R42/43
Safety

Moderately toxic by intravenous route. An experimental teratogen. Human systemic effects: normocytic anemia, leukopenia, hemorrhage. When heated to decomposition it emits toxic fumes of SO_x, NO_x and Na₂O.
Hazard Codes: Xn
Risk Statements: 42/43
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements: 22-36/37-45
S22:Do not breathe dust.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 2
RTECS: XI0180000

Toxicity

dog	LD50	intravenous	> 6gm/kg (6000mg/kg)	?	Japanese Journal of Antibiotics. Vol. 36, Pg. 653, 1983.
monkey	LD50	intravenous	> 4gm/kg (4000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 634, 1982.
mouse	LD50	intraperitoneal	9770mg/kg (9770mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Chemotherapy Vol. 25, Pg. 816, 1977.
mouse	LD50	intravenous	4900mg/kg (4900mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Chemotherapy Vol. 25, Pg. 816, 1977.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 634, 1982.
mouse	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 634, 1982.
rat	LD50	intraperitoneal	7600mg/kg (7600mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Chemotherapy Vol. 25, Pg. 816, 1977.
rat	LD50	intravenous	2260mg/kg (2260mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 884, 1979.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 634, 1982.
rat	LD50	subcutaneous	8800mg/kg (8800mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 884, 1979.
rat	LD50	unreported	2gm/kg (2000mg/kg)	?	United States Patent Document. Vol. #4535078,
women	TDLo	intramuscular	960mg/kg/3D-I (960mg/kg)	BLOOD: HEMORRHAGE	Southern Medical Journal. Vol. 78, Pg. 363, 1985.
women	TDLo	intravenous	2180mg/kg/6D- (2180mg/kg)	BLOOD: NORMOCYTIC ANEMIA BLOOD: LEUKOPENIA	Southern Medical Journal. Vol. 79, Pg. 255, 1986.

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Piperacillin sodium salt cas no:59703-84-3

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