Camostat mesilate cas no:59721-29-8
Synonyms: Camostatum [INN-Latin];Foipan (TN);p-Guanidinobenzoic acid, ester with (p-hydroxyphenyl)acetic acid, ester with N,N-dimethylglycolamide;Benzeneacetic acid, 4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-, 2-(dimethylamino)-2-oxoethyl ester, monomethanesulfonate;FOY 305;diaminomethylidene-[4-[4-(dimethylcarbamoylmethoxycarbonylmethyl)phenoxy]carbonylphenyl]azanium; methanesulfonate;Camostat mesylate;Camostat monomethanesulfonate;[4-(dimethylcarbamoylmethoxycarbonylmethyl)phenyl] 4-(diaminomethylideneamino)benzoate;Camostat [INN];Benzeneacetic acid,4-[[4-[(aminoiminomethyl)- amino]benzoyl]oxy]-,2-(dimethylamino)-2- oxoethyl ester,monomethanesulfonate;p-(p-Guanidinobenzoyloxy)phenyl acetic acid, N,N-dimethylcarbamoylmethyl ester;
NameCamostat mesilate
CAS59721-29-8
SynonymsCamostatum [INN-Latin];Foipan (TN);p-Guanidinobenzoic acid, ester with (p-hydroxyphenyl)acetic acid, ester with N,N-dimethylglycolamide;Benzeneacetic acid, 4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-, 2-(dimethylamino)-2-oxoethyl ester, monomethanesulfonate;FOY 305;diaminomethylidene-[4-[4-(dimethylcarbamoylmethoxycarbonylmethyl)phenoxy]carbonylphenyl]azanium; methanesulfonate;Camostat mesylate;Camostat monomethanesulfonate;[4-(dimethylcarbamoylmethoxycarbonylmethyl)phenyl] 4-(diaminomethylideneamino)benzoate;Camostat [INN];Benzeneacetic acid,4-[[4-[(aminoiminomethyl)- amino]benzoyl]oxy]-,2-(dimethylamino)-2- oxoethyl ester,monomethanesulfonate;p-(p-Guanidinobenzoyloxy)phenyl acetic acid, N,N-dimethylcarbamoylmethyl ester;
Molecular FormulaC20H22N4O5.CH4O3S
Molecular Weight494.52
Appearancecrystalline solid
storage tempDesiccate at RT
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CY1571620
- CHEMICAL NAME :
- Benzeneacetic acid,
4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-,
2-(dimethylamino)-2- oxoethyl ester,
monomethanesulfonate
- CAS REGISTRY NUMBER :
- 59721-29-8
- LAST UPDATED :
- 198708
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C20-H22-N4-O5.C-H4-O3-S
- MOLECULAR WEIGHT :
- 494.57
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 27,719,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 16,590,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 152 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 16,590,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka
Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-
Volume(issue)/page/year: 27,719,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 16,590,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho
Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-
Volume(issue)/page/year: 16,590,1985
