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5-Isobenzofurancarbonitrile,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro- cas no:59729-33-8

Synonyms: 1-(3-Dimethylaminopropyl)-1-(4-fluorophenyl)-5-cyanophthalan;1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile;Bonitrile;Lu 10-171;Nitalapram;

Identification
Name5-Isobenzofurancarbonitrile,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-
CAS59729-33-8
Synonyms1-(3-Dimethylaminopropyl)-1-(4-fluorophenyl)-5-cyanophthalan;1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile;Bonitrile;Lu 10-171;Nitalapram;
EINECS(EC#)261-891-1
Molecular FormulaC20H21FN2O
Molecular Weight324.391943
Chemical Properties
Appearancewhite to off-white crystalline powder
storage tempKeep tightly closed. Store at 2-8 C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard UN NO.
Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo oral 4571ug/kg/8D- (4.571mg/kg) BEHAVIORAL: SLEEP

BEHAVIORAL: HEADACHE

GASTROINTESTINAL: NAUSEA OR VOMITING
Human Psychopharmacology. Vol. 12, Pg. 119, 1997.
man LDLo oral 56mg/kg (56mg/kg) CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) Lancet. Vol. 348, Pg. 339, 1996.
mouse LD50 intraperitoneal 179mg/kg (179mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmacy and Pharmacology. Vol. 49, Pg. 1019, 1997.

supplier list

Vinchem, Inc.
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Qilong Chemical Co., Ltd.
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Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,
S.S.T. Corporation
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Sris Pharmaceuticals
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Hangzhou Starshine Pharmaceutical Co., Ltd.
Tel:+86-(571)-8993-9756, 8993-6036
Address: Room A, 20th Floor, West Building, International Garden, No.160 Tianmusan Road, Hangzhou 310006,
Nanjing Hicin Pharmaceutical Co., Ltd.
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Address: 70# Matai Street, Nanjing, Jiangsu 210009,
LKT Laboratories, Inc.
Tel:+1-(651)-644-8357
Address: 2233 University Avenue West, St. Paul, Minnesota 55114-1629,
HangZhou Peak Chemical Co.,Ltd
Tel:+86-571-88233073
Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China
Yann Pharmachem Co., Ltd.
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Address: Room 503, Building 9, Linping Road, Shanghai
AOPHARM
Tel:86-311-66600578
Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.
Wuhan Senwayer Century chemical Co.,Ltd
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Address: 20#Xudong Street,Wuhan China
Hangzhou Dayangchem Co., Ltd.
Tel:86-571-88938639
Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road
Hangzhou J&H Chemical Co., Ltd
Tel:86-571-87396430
Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China
Finetech Industry limited.
Tel:86-27-87465837
Address: chukang Road, Wuhan, Hubei 430073,
HUTONG GLOBAL CO.,LTD
Tel:86-22-59853797
Address: chagugang,wuqing district,Tianjin,China

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