4-Hydroxyestradiol cas no:5976-61-4

Name4-Hydroxyestradiol
CAS5976-61-4
Synonyms3,4,17BETA-TRIHYDROXY-1,3,5[10]-ESTRATRIENE;1,3,5[10]-ESTRATRIENE-3,4,17BETA-TRIOL;1,3,5(10)-ESTRATRIEN-3,4,17-BETA-TRIOL;4-HYDROXY 17-BETA-ESTRADIOL;4-HYDROXYESTRADIOL;4-hydroxyestradiol-17beta;4-oh-estradiol;estra-1,3,5(10)-triene-3,4,17-beta-triol
Molecular FormulaC18H24O3
Molecular Weight288.38

refractive index1.622
storage temp−20°C

Hazard Xn
Risk 40
Safety

Experimental reproductive data. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: Xn
Risk Statements: 40 
R40: Limited evidence of a carcinogenic effect.
Safety Statements: 22-36 
S22: Do not breathe dust. 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: KG7676000

1.		Rodent - ratDOSE : 1280 ng/kgSEX/DURATION		ANDRDQ Andrologia. (Grosse Verlag GmbH, Kurfuerstenstr. 112-113, D-1000 Berlin 30, Fed. Rep. Ger.) V.6- 1974- Volume(issue)/page/year: 23,339,1991
2.		Rodent - ratDOSE : 10 ug/kgSEX/DURATION		EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 42,165,1986
3.		Rodent - hamster: 14 mg/kg/7D (Continuous)		CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 15,997,1994