Tenoxicam cas no:59804-37-4
Synonyms: Tenoxicam (JAN/USAN);Ro 12-0068/000;Tilcotil (TN);Tenoxicam [USAN:BAN:INN:JAN];2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide;Tenoxicamum [INN-Latin];(3Z)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-4-methyl-5,5-dioxo-5$l^{6},9-dithia-4-azabicyclo[4.3.0]nona-7,10-dien-2-one;Ro 12-0068;Prestwick_849;4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide;Tilcotil;Tenoxicam CP EP;4-Hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide-1,1-dioxide;
NameTenoxicam
CAS59804-37-4
SynonymsTenoxicam (JAN/USAN);Ro 12-0068/000;Tilcotil (TN);Tenoxicam [USAN:BAN:INN:JAN];2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide;Tenoxicamum [INN-Latin];(3Z)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-4-methyl-5,5-dioxo-5$l^{6},9-dithia-4-azabicyclo[4.3.0]nona-7,10-dien-2-one;Ro 12-0068;Prestwick_849;4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide;Tilcotil;Tenoxicam CP EP;4-Hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide-1,1-dioxide;
EINECS(EC#)安全数据
Molecular FormulaC13H11N3O4S2
Molecular Weight337.37
Appearanceyellow crystalline powder
refractive index1.741
storage tempStore in original container in a cool dark place.
Hazard T:Toxic
Risk R23/24/25
Safety
Hazard Codes:?
T,
Xi
Risk Statements: 23/24/25-36/37/38?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 36/37/39-45-36-26?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
RTECS: XJ9095060
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD50 |
oral |
> 128mg/kg (128mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 1030, 1987. |
| mouse |
LD50 |
intraperitoneal |
446mg/kg (446mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl, |
| mouse |
LD50 |
oral |
297mg/kg (297mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl, |
| mouse |
LD50 |
subcutaneous |
449mg/kg (449mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl, |
| rat |
LD50 |
intraperitoneal |
234mg/kg (234mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl, |
| rat |
LD50 |
oral |
79mg/kg (79mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl, |
| rat |
LD50 |
subcutaneous |
186mg/kg (186mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl, |
