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Vindesine Sulfate cas no:59917-39-4

Synonyms: Desacetylvinblastine amide sulfate (1:1)

Identification
NameVindesine Sulfate
CAS59917-39-4
SynonymsDesacetylvinblastine amide sulfate (1:1)
EINECS(EC#)261-984-7
Molecular FormulaC43H55N5O7.H2SO4
Molecular Weight852.00458
Chemical Properties
AppearanceAmorphous Solid
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard Xn: Harmful;
Risk R40
Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.

Hazard codes: Xn Harmful
Risk statements: 40 Limited evidence of a carcinogenic effect. 
Safety statements: 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
                           36 Wear suitable protective clothing. 


Toxicity

mouse LD50 intraperitoneal 3500ug/kg (3.5mg/kg) BEHAVIORAL: ATAXIA
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
mouse LD50 intravenous 6300ug/kg (6.3mg/kg)   Journal of Toxicology and Environmental Health. Vol. 1, Pg. 843, 1976.
mouse LD50 subcutaneous 6800ug/kg (6.8mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
rat LD50 intraperitoneal 1050ug/kg (1.05mg/kg) BEHAVIORAL: ATAXIA
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
rat LD50 intravenous 1920ug/kg (1.92mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BLOOD: NORMOCYTIC ANEMIA
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.
rat LD50 subcutaneous 1790ug/kg (1.79mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 17, Pg. 1549, 1983.

supplier list

Fine Chem Trading LTD
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CHONGQING TRUST LONG CO.,LTD.
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Sunji & Co., Ltd.
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SINOCO CHEMICAL CO., LIMITED
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Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.
HANGZHOU THINK CHEMICAL CO., LTD.
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Shanghai Richem International Co., Ltd.
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Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road, Pudong, Shanghai 200135,
Yingxuan Chempharm Co., Ltd.
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Chongqing Trust Long Co., Ltd.
Tel:+86-(23)-6760-5657, 6791-0421, 6707-4306
Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist, Chongqing 401147,
Changzhou Gaoxuan Imp. & Exp. Co., Ltd.
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Address: Rm 1519, ECO International Ditital Plaza ,No.38, Guanhe East Road, Changzhou, Jiangsu,
Beijing HuameiHuli Biochem Ltd
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Address: Beijing TongZhou District
HangZhou Peak Chemical Co.,Ltd
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Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China
Microchem
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Wuxi Sunfu Pharma Co.ltd
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Shanghai Hope Chem Co., Ltd.
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Address: Room508, Building1, No.88 CaiLun Road Zhangjiang H
Nanjing Chemlin Chemical Co., Ltd.
Tel:86-25-83697070
Address: Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

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