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STRYCHNINE SULFATE (2:1) cas no:60-41-3

Synonyms: strychninesulphate;Strychninesulfate;97%;Strychninesulfate

Identification
NameSTRYCHNINE SULFATE (2:1)
CAS60-41-3
Synonymsstrychninesulphate;Strychninesulfate;97%;Strychninesulfate
EINECS(EC#)200-477-7
Molecular FormulaC21H22N2O2•1/2H2O4S
Molecular Weight383.49
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard T+,N
Risk 27/28-50/53-26/28
Safety

Hazard Codes:  T+,N
Risk Statements: 26/27/28-50/53
26/27/28:  Very Toxic by inhalation, in contact with skin and if swallowed
50/53:  Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment  
Safety Statements:  36/37-45-60-61-28-13
13:  Keep away from food, drink and animal feeding stuffs
28:  After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet
36/37:  Wear suitable protective clothing and gloves 
RIDADR:  UN 1692 6.1/PG 1
WGK Germany:  3
RTECS : WL2550000
HazardClass:  6.1(a)
PackingGroup  I


Toxicity

 

Organism

Test Type

Route

Reported Dose (Normalized Dose)

Effect

Source

bird - wild

LD50

oral

5600ug/kg (5.6mg/kg)

 

Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.

cat

LD50

intravenous

2500ug/kg (2.5mg/kg)

 

Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 316, 1936.

child

LDLo

oral

3367ug/kg (3.367mg/kg)

behavioral: general anesthetic
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: acute pulmonary edema

Journal of Forensic Sciences. Vol. 30, Pg. 1248, 1985.

guinea pig

LD50

intraperitoneal

10900ug/kg (10.9mg/kg)

behavioral: convulsions or effect on seizure threshold

Archives Internationales de Pharmacodynamie et de Therapie. Vol. 144, Pg. 416, 1963.

guinea pig

LD50

intravenous

390ug/kg (0.39mg/kg)

behavioral: convulsions or effect on seizure threshold

Archives Internationales de Pharmacodynamie et de Therapie. Vol. 144, Pg. 416, 1963.

guinea pig

LD50

subcutaneous

4800ug/kg (4.8mg/kg)

behavioral: convulsions or effect on seizure threshold

Archives Internationales de Pharmacodynamie et de Therapie. Vol. 144, Pg. 416, 1963.

man

LDLo

oral

37mg/kg (37mg/kg)

behavioral: convulsions or effect on seizure threshold
cardiac: pulse rate
lungs, thorax, or respiration: pleural thickening

Journal of Analytical Toxicology. Vol. 10, Pg. 120, 1986.

mouse

LD50

intraperitoneal

900ug/kg (0.9mg/kg)

 

International Journal for Vitamin and Nutrition Research, Supplement. Vol. 16, Pg. 31, 1977.

mouse

LD50

intravenous

475ug/kg (0.475mg/kg)

 

Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 127, 1943.

mouse

LD50

subcutaneous

1250ug/kg (1.25mg/kg)

 

Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 153, 1939.

mouse

LDLo

oral

8mg/kg (8mg/kg)

 

Archives of Environmental Contamination and Toxicology. Vol. 14, Pg. 111, 1985.

rat

LD50

intraperitoneal

1mg/kg (1mg/kg)

behavioral: convulsions or effect on seizure threshold

Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 1125, 1973.

rat

LD50

intravenous

570ug/kg (0.57mg/kg)

behavioral: convulsions or effect on seizure threshold

Archives Internationales de Pharmacodynamie et de Therapie. Vol. 144, Pg. 416, 1963.

rat

LD50

oral

2600ug/kg (2.6mg/kg)

 

Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 113, 1942.

rat

LD50

subcutaneous

1700ug/kg (1.7mg/kg)

 

Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.

women

TDLo

oral

6800ug/kg (6.8mg/kg)

behavioral: convulsions or effect on seizure threshold
behavioral: changes in motor activity (specific assay)
blood: other changes

Canadian Medical Association Journal. Vol. 124, Pg. 1268, 1981.

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