4-Thiazolecarboxamide,2-b-D-ribofuranosyl- cas no:60084-10-8

Name4-Thiazolecarboxamide,2-b-D-ribofuranosyl-
CAS60084-10-8
Synonyms2-b-D-Ribofuranosylthiazole-4-carboxamide;CI 909; NSC 286-193; NSC 286193; Riboxamide; TCAR; Tiazofurin; Tiazofurine
Molecular FormulaC9H12 N2 O5 S
Molecular Weight260.29

refractive index1.674

Safety

Moderately toxic by intravenous and intraperitoneal routes. Human systemic effects by intravenous route: headache, convulsions, and musculo-skeletal changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SO_x and NO_x.

1.		dni-mus:lym 10 µmol/L		CNREA8    Cancer Research. 45 (1985),5512.
2.		dni-mus:leu 10 µmol/L		BCPCA6    Biochemical Pharmacology. 34 (1985),1109.
3.		ivn-hmn TDLo:1135 mg/kg/15D-I:CNS,MSK		CNREA8    Cancer Research. 45 (1985),5169.
4.		ivn-hmn TDLo:892 mg/kg/10D-I:CNS		CNREA8    Cancer Research. 45 (1985),5169.
5.		ipr-mus LD50:1684 mg/kg		NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
6.		ivn-mus LD50:3400 mg/kg		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 .
7.		ivn-dog LDLo:1090 mg/kg		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB83-156901 .