60166-93-0|IopamidolProducts Supply - Chemical intermediates Network

Iopamidol cas no:60166-93-0

Synonyms: 1,3-Benzenedicarboxamide,N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-,(S)-;1,3-Benzenedicarboxamide,N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-(9CI);Gastromiro;Iopamidol 300;Iopamiro;Iopamiro 370;Iopamiron 300;Iopamiron 370;Isovue;Isovue 300;Isovue 370;Jopamiron 200;Niopam;Niopam 300;Oypalomin;Oypalomin 150;Solutrast;Solutrast 370;

Identification

NameIopamidol
CAS60166-93-0
Synonyms1,3-Benzenedicarboxamide,N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-,(S)-;1,3-Benzenedicarboxamide,N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[[(2S)-2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-(9CI);Gastromiro;Iopamidol 300;Iopamiro;Iopamiro 370;Iopamiron 300;Iopamiron 370;Isovue;Isovue 300;Isovue 370;Jopamiron 200;Niopam;Niopam 300;Oypalomin;Oypalomin 150;Solutrast;Solutrast 370;
EINECS(EC#)262-093-6
Molecular FormulaC₁₇H₂₂I₃N₃O₈
Molecular Weight777.12

Chemical Properties

AppearanceWhite Crystalline Powder
alpha- 4.6°~ - 5.2°
refractive index1.738
storage temp-20?C Freezer

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	35gm/kg (35000mg/kg)	?	Farmaco, Edizione Scientifica. Vol. 32, Pg. 835, 1977.
man	TDLo	intraspinal	214uL/kg (0.214mL/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP	American Journal of Emergency Medicine. Vol. 12, Pg. 329, 1994.
man	TDLo	intravenous	600mg/kg/3S-C (600mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) CARDIAC: CHANGE IN RATE	Archives of Internal Medicine. Vol. 147, Pg. 2208, 1987.
man	TDLo	intravenous	1657mg/kg (1657mg/kg)	KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"	Annals of Internal Medicine. Vol. 107, Pg. 116, 1987.
mouse	LD50	intracrebral	3gm/kg (3000mg/kg)	?	Farmaco, Edizione Scientifica. Vol. 32, Pg. 835, 1977.
mouse	LD50	intraperitoneal	40825mg/kg (40825mg/kg)	?	United States Patent Document. Vol. #4001323,
mouse	LD50	intravenous	33gm/kg (33000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl,
mouse	LD50	oral	> 49gm/kg (49000mg/kg)	?	Drugs in Japan Vol. -, Pg. 104, 1990.
mouse	LD50	subcutaneous	> 49gm/kg (49000mg/kg)	?	Drugs in Japan Vol. -, Pg. 104, 1990.
rabbit	LD50	intravenous	20gm/kg (20000mg/kg)	?	Farmaco, Edizione Scientifica. Vol. 32, Pg. 835, 1977.
rabbit	LD50	parenteral	510mg/kg (510mg/kg)	?	United States Patent Document. Vol. #4001323,
rabbit	LD50	unreported	> 245mg/kg (245mg/kg)	?	Journal of the American College of Toxicology. Vol. 9, Pg. 563, 1990.
rat	LD	oral	> 49gm/kg (49000mg/kg)	?	Farmaco, Edizione Scientifica. Vol. 32, Pg. 835, 1977.
rat	LD50	intraarterial	13268mg/kg (13268mg/kg)	?	United States Patent Document. Vol. #4001323,
rat	LD50	intracrebral	2449mg/kg (2449mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 45, Pg. 200, 1995.
rat	LD50	intraperitoneal	35gm/kg (35000mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl,
rat	LD50	intravenous	22044mg/kg (22044mg/kg)	?	Acta Radiologica, Supplementum. Vol. 370, Pg. 41, 1987.
rat	LD50	subcutaneous	> 49gm/kg (49000mg/kg)	?	Drugs in Japan Vol. -, Pg. 104, 1990.
rat	LDLo	parenteral	2041mg/kg (2041mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22, Pg. 769, 1994.

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Leawell International Limited: Tel:+852-(2576)-0298; Address: 18/F Catic Plaza, 8 Causeway Road Causeway Bay,

Smruthi Organics Ltd.: Tel:+91-(217)-231 0267, 231 0367; Address: 165A Balaji Bhavan, Railway Lines, Solapur, Maharashtra 413001,

Credimate Trading Limited: Tel:+86-(21)-57429129; Address: Suite 302, No. 503 Guhuaxincun Area B, Nanqiao, Fengxian, Shanghai 201400,

Sanmen Eastsky Pharmaceutical Co., Ltd: Tel:+86-(576)-83510058; Address: Room 8402, Saigete Garden, Dahutang Development Zone, Sanmen, Zhejiang 317100,

Ningbo Sinova Import/Export Corp.: Tel:; Address:

Kouting Chemical Co.,Ltd: Tel:+86-(21)-58116473; Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318,

Fine & Performance Chemicals Ltd: Tel:+44 (0) 1642 710106; Address: Ellerbeck Way Stokesley Industrial Park Stokesley Middlesbrough TS9 5JZ UK

SYNERGETICA: Tel:1 517 552 7471; Address: United States

Wujiang Yingchuang Chemical Co., Ltd.: Tel:+86-(25)-8645 8768; Address: 215 Ying Tian Da Street, JianYe, Nanjing, Jiangsu 210017,

Shanghai Hope Chem Co., Ltd.: Tel:86-21-61723543; Address: Room508, Building1, No.88 CaiLun Road Zhangjiang H

Struchem Co Ltd: Tel:86-512-63009836; Address: No. 2358 Chang'an Rd, Wujiang City, JiangSu Province, China 215200

Jinlan Pharm-Drugs Technology Co., Limited: Tel:86-571-85829152; Address: Room 606, Fuyi Center, #298 Quanfuqiao Road, Jiang

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hangzhou UNIWISE International Co.,Ltd.: Tel:+86-571-28819531; Address: E-19F, Dongqiing Building, 52 Qingchun Rd, Hangzhou, China

Iopamidol cas no:60166-93-0

Directory

supplier list