605-23-2|2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-methyl-Products Supply

2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-methyl- cas no:605-23-2

Synonyms: Thymine,1-b-D-arabinofuranosyl-(6CI,7CI,8CI);1-b-DArabinofuranosylthymine;1-b-D-Arabinofuranosylthymine;5-Methylarabinosyluracil;Ara-T;Arabinosylthymine;NSC 68929;Spongothymidin;Spongothymidine;Thyminearabinoside;

Identification

Name2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-methyl-
CAS605-23-2
SynonymsThymine,1-b-D-arabinofuranosyl-(6CI,7CI,8CI);1-b-DArabinofuranosylthymine;1-b-D-Arabinofuranosylthymine;5-Methylarabinosyluracil;Ara-T;Arabinosylthymine;NSC 68929;Spongothymidin;Spongothymidine;Thyminearabinoside;
EINECS(EC#)210-083-7
Molecular FormulaC₁₀H₁₄N₂O₆
Molecular Weight 258.23

Chemical Properties

refractive index1.618
storage temp2-8°C

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XP2100200

CHEMICAL NAME :: Thymine, 1-beta-D-arabinofuranosyl-

CAS REGISTRY NUMBER :: 605-23-2

BEILSTEIN REFERENCE NO. :: 0090166

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C10-H14-N2-O6

MOLECULAR WEIGHT :: 258.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 7100 ug/L

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 23,141,1978

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