frog |
LDLo |
subcutaneous |
1gm/kg (1000mg/kg) |
AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
CARDIAC: PULSE RATE
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903. |
mouse |
LD50 |
intraperitoneal |
330mg/kg (330mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: CYANOSIS |
Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967. |
mouse |
LD50 |
intravenous |
160mg/kg (160mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 36, 1957. |
mouse |
LDLo |
subcutaneous |
657mg/kg (657mg/kg) |
AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
LUNGS, THORAX, OR RESPIRATION: CYANOSIS |
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903. |
rat |
LD50 |
oral |
133mg/kg (133mg/kg) |
|
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 289, 1972. |