61-12-1|Dibucaine HydrochlorideProducts Supply - Chemical intermediates Network

Dibucaine Hydrochloride cas no:61-12-1

Synonyms: 4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (9CI);Cinchoninamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (8CI);2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;2-Butoxy-N-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride;2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;Benzolin (local anesthetic);Cincaine;Cincaine chloride;Cinchocainehydrochloride;Cinchocainium chloride;Nupercainehydrochloride;Percain;Percaine;Percamin S;Sovcain;Sovcaine;

Identification

NameDibucaine Hydrochloride
CAS61-12-1
Synonyms4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (9CI);Cinchoninamide,2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride (8CI);2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;2-Butoxy-N-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride;2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride;Benzolin (local anesthetic);Cincaine;Cincaine chloride;Cinchocainehydrochloride;Cinchocainium chloride;Nupercainehydrochloride;Percain;Percaine;Percamin S;Sovcain;Sovcaine;
EINECS(EC#)200-498-1
Molecular FormulaC₂₀H₃₀ClN₃O₂
Molecular Weight379.93

Chemical Properties

Appearancewhite powder
storage tempRefrigerator

Safety Data

Hazard Xn:Harmful
Risk R22;R41
Safety

Poison by ingestion, subcutaneous, intravenous, intraspinal, parenteral, and intraperitoneal routes. Mutation data reported. A severe eye irritant. A local anesthetic. When heated to decomposition it emits very toxic fumes of HCl and NO_x
Safety Information of Dibucaine Hydrochloride (CAS NO.61-12-1):
Hazard Codes: Xn
Xn: Harmful
Risk Statements: 22-41
22: Harmful if swallowed
41: Risk of serious damage to eyes
Safety Statements: 26-39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
39: Wear eye/face protection
WGK Germany: 3
RTECS: GD3325000

Toxicity

1.	eye-rbt 2% SEV	ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),181.
2.	dnd-esc 15 µmol/L	MUREAV Mutation Research. 89 (1981),95.
3.	ipr-rat LD50:30 mg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 103 (1951),306.
4.	scu-rat LD50:27 mg/kg	DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews .(ADIS Press Ltd.,Wanchai, Hong Kong.: )1990,478.
5.	ivn-rat LD50:52 mg/kg	DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews .(ADIS Press Ltd.,Wanchai, Hong Kong.: )1990,478.
6.	ipr-mus LD50:29 mg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 94 (1948),299.
7.	scu-mus LD50:25,400 µg/kg	PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 103 (1960),353.
8.	ivn-mus LD50:5151 µg/kg	JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. 44 (1955),393.
9.	scu-rbt LDLo:5 mg/kg	ODFU** Vergleichende pharmakologische Prufung Zweier neuer Lokalanas-thetika: Perkain und Pantokain, Wilhelm Ost Dissertation .(Pharmakologischen Institut der Universitat zu Frankfurt am Ma

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Dibucaine Hydrochloride cas no:61-12-1

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