2-Imidazolidinone,1-(5-nitro-2-thiazolyl)- cas no:61-57-4

Name2-Imidazolidinone,1-(5-nitro-2-thiazolyl)-
CAS61-57-4
Synonyms1-(5-Nitro-1,3-thiazol-2-yl)-2-imidazolidinone;1-(5-Nitro-2-thiazolyl)-2-imidazolidinone; 1-(5-Nitro-2-thiazolyl)-2-imidazolinone;1-(5-Nitro-2-thiazolyl)-2-oxotetrahydroimidazole; Ambilhar; Ba 32644; Ciba32644; Ciba 32644Ba; NSC 136947; Niridazole; Nitrothiamidazol;Nitrothiamidazole; Nitrothiazol; Nitrothiazole
EINECS(EC#)200-512-6
Molecular FormulaC6H6 N4 O3 S
Molecular Weight214.22

refractive index1.614

Safety

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. Used as an amoebicide and schistosomicidal agent. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.

1.		mma-sat 33 ng/plate		ENMUDM    Environmental Mutagenesis. 7 (1985),429.
2.		bfa-hmn/sat 25 mg/kg		CMMUAO    Chemical Mutagens. Principles and Methods for Their Detection 4 (1976),171.
3.		orl-mus TDLo:175 mg/kg (male 5D pre):REP		JRPFA4    Journal of Reproduction and Fertility. 46 (1976),217.
4.		orl-rat TDLo:8 g/kg/90W-I:NEO		CALEDQ    Cancer Letters (Shannon, Ireland). 4 (1978),305.
5.		orl-mus TDLo:15 g/kg/49W-C:CAR		CALEDQ    Cancer Letters (Shannon, Ireland). 1 (1975),69.
6.		orl-mus TD:16 g/kg/75W-C:CAR		JNCIAM    Journal of the National Cancer Institute. 59 (1977),1625.
7.		orl-rat LD50:900 mg/kg		FAZMAE    Fortschritte der Arzneimittelforschung. 17 (1973),108.
8.		orl-mus LD50:2500 mg/kg		YHHPAL    Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. 15 (1980),456.
9.		ipr-mus LD50:220 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 228 (1984),662.