Phenothiazin-5-ium,3,7-bis(dimethylamino)-, chloride (1:1) cas no:61-73-4
Synonyms: C.I. BasicBlue 9 (6CI,8CI);Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride (9CI);Basic Blue 9;C.I. Solvent Blue 8;Calcozine Blue ZF;Izit Crystal Dye;Leather Pure Blue HB;Methylene Blue 2B;Methylene Blue 2BN;Methylene Blue2BP;Methylene Blue A;Methylene Blue BB;Methylene Blue BP;Methylene Blue BPC;Methylene Blue BX;Methylene Blue FZ;Methylene Blue G;MethyleneBlue SG;Methylene Blue SP;Methylene Blue ZF;Methylene Blue ZX;Methylene bluepolychrome;NSC 617593;Sandocryl Blue BRL;Schultz 1038;Solvent Blue 8;Tetramethylthioninechloride;Urolene Blue;Virostat;Yamamoto Methylene Blue B;Yamamoto MethyleneBlue ZF;
NamePhenothiazin-5-ium,3,7-bis(dimethylamino)-, chloride (1:1)
CAS61-73-4
SynonymsC.I. BasicBlue 9 (6CI,8CI);Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride (9CI);Basic Blue 9;C.I. Solvent Blue 8;Calcozine Blue ZF;Izit Crystal Dye;Leather Pure Blue HB;Methylene Blue 2B;Methylene Blue 2BN;Methylene Blue2BP;Methylene Blue A;Methylene Blue BB;Methylene Blue BP;Methylene Blue BPC;Methylene Blue BX;Methylene Blue FZ;Methylene Blue G;MethyleneBlue SG;Methylene Blue SP;Methylene Blue ZF;Methylene Blue ZX;Methylene bluepolychrome;NSC 617593;Sandocryl Blue BRL;Schultz 1038;Solvent Blue 8;Tetramethylthioninechloride;Urolene Blue;Virostat;Yamamoto Methylene Blue B;Yamamoto MethyleneBlue ZF;
EINECS(EC#)200-515-2
Molecular FormulaC16H18ClN3S
Molecular Weight319.85222
Appearancegreen fine crystalline powder
storage tempStore at RT
Hazard Xn:Harmful
Risk R22;R41
Safety Hazard Codes:Xn
Risk Statements:10-41-22-20/21/22
10:Flammable
41:Risk of serious damage to eyes
22:Harmful if swallowed
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
Safety Statements:26-39-36
26:In case of contact with eyes, rinse immediately with plenty
of water and seek medical advice
39:Wear eye/face protection
36:Wear suitable protective clothing
RIDADR:UN 1993 3/PG 3
WGK Germany:3
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO5600000
- CHEMICAL NAME :
- 3H-Phenothiazine, 7-(dimethylamino)-3-(methylimino)-,
3-methochloride
- CAS REGISTRY NUMBER :
- 61-73-4
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 36
- MOLECULAR FORMULA :
- C16-H18-N3-S.Cl
- MOLECULAR WEIGHT :
- 319.88
- WISWESSER LINE NOTATION :
- T C666 BS EY INJ EUK1&1 MN1&1 &G &421
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - infant
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis
Blood - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 190 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 77 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 41 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 42300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2500 mg/kg
- SEX/DURATION :
- female 1-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 1830 nmol/L
- REFERENCE :
- BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY
10158) V.1- 1963- Volume(issue)/page/year: 12,1099,1973
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M1469
No. of Facilities: 4471 (estimated)
No. of Industries: 35
No. of Occupations: 34
No. of Employees: 25916 (estimated)
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - T1406
No. of Facilities: 150 (estimated)
No. of Industries: 2
No. of Occupations: 2
No. of Employees: 664 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M1469
No. of Facilities: 5956 (estimated)
No. of Industries: 29
No. of Occupations: 51
No. of Employees: 74208 (estimated)
No. of Female Employees: 43305 (estimated)
