2-Benzoxazolamine,5-chloro- cas no:61-80-3
Synonyms: Benzoxazole,2-amino-5-chloro- (6CI,8CI); 2-Amino-5-chlorobenzoxazole;5-Chloro-1,3-benzoxazol-2-amine; 5-Chloro-2-aminobenzoxazole;5-Chlorobenzoxazol-2-amine; 5-Chlorobenzoxazol-2-ylamine; Deflexol; Flexilon;Flexin; McN-485; NSC 24995; Zoxamin; Zoxazolamine; Zoxine
Name2-Benzoxazolamine,5-chloro-
CAS61-80-3
SynonymsBenzoxazole,2-amino-5-chloro- (6CI,8CI); 2-Amino-5-chlorobenzoxazole;5-Chloro-1,3-benzoxazol-2-amine; 5-Chloro-2-aminobenzoxazole;5-Chlorobenzoxazol-2-amine; 5-Chlorobenzoxazol-2-ylamine; Deflexol; Flexilon;Flexin; McN-485; NSC 24995; Zoxamin; Zoxazolamine; Zoxine
EINECS(EC#)200-519-4
Molecular FormulaC7H5 Cl N2 O
Molecular Weight168.58
refractive index1.692
storage tempRefrigerator
Hazard Xn:Harmful;
Risk R20/21/22;R36/37/38
Safety
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Human systemic effects by ingestion: muscle rigidity. When heated to decomposition it yields toxic fumes of Cl− and NOx.
Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
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orl-hmn TDLo:14 mg/kg/D:CNS
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JAMAAP JAMA, Journal of the American Medical Association. 160 (1956),745. |
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orl-rat LD50:782 mg/kg
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FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. 16 (1957),319. |
| 3. |
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ipr-rat LD50:102 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 129 (1960),75. |
| 4. |
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orl-mus LD50:540 mg/kg
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 128 (1960),112. |
| 5. |
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ipr-mus LD50:100 mg/kg
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NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 . |
| 6. |
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ivn-mus LD50:376 mg/kg
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29QHAQ Principles of Medicinal Chemistry Foye, W.O., eds.,Philadelphia, PA.: Lea and Febiger,1974,74. |
| 7. |
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ivn-dog LD50:117 mg/kg
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FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. 16 (1957),319. |
| 8. |
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orl-ham LD50:670 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 129 (1960),75. |
| 9. |
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ipr-ham LD50:268 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 129 (1960),75. |
Carcinogenicity of 2-Amino-5-chlorobenzoxazole (CAS.61-80-3) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. You can see actual entry in RTECS for complete information.
