Benzenemethanamine,2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, hydrochloride (1:1) cas no:611-75-6
Synonyms: Benzenemethanamine,2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, monohydrochloride (9CI);Toluene-a,2-diamine,3,5-dibromo-Na-cyclohexyl-Na-methyl-, monohydrochloride (8CI);2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine monohydrochloride;Auxit;Bisolvon;Bisolvon hydrochloride;Bromhexine chloride;Bromhexine monohydrochloride;Cyclohexylmethyl(2-amino-3,5-dibromobenzyl)ammonium chloride;N-Cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)ammonium chloride;N-Cyclohexyl-N-methyl-N-(2-amino-3,5-dibromobenzyl)ammonium chloride;Na-Cyclohexyl-Na-methyl-3,5-dibromotoluene-a,2-diaminehydrochloride;Ophtosol;Quentan;
NameBenzenemethanamine,2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, hydrochloride (1:1)
CAS611-75-6
SynonymsBenzenemethanamine,2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, monohydrochloride (9CI);Toluene-a,2-diamine,3,5-dibromo-Na-cyclohexyl-Na-methyl-, monohydrochloride (8CI);2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine monohydrochloride;Auxit;Bisolvon;Bisolvon hydrochloride;Bromhexine chloride;Bromhexine monohydrochloride;Cyclohexylmethyl(2-amino-3,5-dibromobenzyl)ammonium chloride;N-Cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)ammonium chloride;N-Cyclohexyl-N-methyl-N-(2-amino-3,5-dibromobenzyl)ammonium chloride;Na-Cyclohexyl-Na-methyl-3,5-dibromotoluene-a,2-diaminehydrochloride;Ophtosol;Quentan;
EINECS(EC#)210-280-8
Molecular FormulaC14H20Br2N2.HCl
Molecular Weight412.59
AppearanceWhite Solid
storage temp2-8°C
Hazard Xn
Risk R20/21/22
Safety
Hazard Codes?
Xn
Risk Statements 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 22-24/25-36-26
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
WGK Germany 2
RTECS XS9950000
HS Code 29215990
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
2210mg/kg (2210mg/kg) |
? |
Gendai no Rinsho. Vol. 3, Pg. 259, 1969. |
| mouse |
LD50 |
intravenous |
44mg/kg (44mg/kg) |
? |
Gendai no Rinsho. Vol. 3, Pg. 259, 1969. |
| mouse |
LD50 |
oral |
3gm/kg (3000mg/kg) |
? |
Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. Vol. 109, Pg. 385, 1970. |
| mouse |
LD50 |
subcutaneous |
> 14gm/kg (14000mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 737, 1982. |
| rabbit |
LD50 |
oral |
10gm/kg (10000mg/kg) |
CARDIAC: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 163, Pg. 284, 1966. |
| rat |
LD50 |
intraperitoneal |
1680mg/kg (1680mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: ATAXIA |
Gendai no Rinsho. Vol. 3, Pg. 259, 1969. |
| rat |
LD50 |
oral |
6gm/kg (6000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: ATAXIA |
Gendai no Rinsho. Vol. 3, Pg. 259, 1969. |
| rat |
LD50 |
subcutaneous |
> 14gm/kg (14000mg/kg) |
? |
Yakkyoku. Pharmacy. Vol. 35(1), Pg. -, 1984. |
