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Potassium clavulanate cas no:61177-45-5

Synonyms: 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)- (9CI);4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, [2R-(2a,3Z,5a)]-;Clavitesse;Clavulanate potassium;Clavulanic acid potassium salt;4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-(2-hydroxyethylidene)-7-oxo-, potassium salt (1:1), (2R,3Z,5R)-;

Identification
NamePotassium clavulanate
CAS61177-45-5
Synonyms4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)- (9CI);4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, [2R-(2a,3Z,5a)]-;Clavitesse;Clavulanate potassium;Clavulanic acid potassium salt;4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-(2-hydroxyethylidene)-7-oxo-, potassium salt (1:1), (2R,3Z,5R)-;
EINECS(EC#)262-640-9
Molecular FormulaC8H8KNO5
Molecular Weight199.16076
Chemical Properties
AppearancePale Yellowish Solid
storage temp2-8°C
Safety Data

Safety

Moderately toxic by intraperitoneal and subcutaneous routes. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Na2O and K2O.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular > 2gm/kg (2000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Chemotherapy Vol. 34(Suppl,
mouse LD50 intraperitoneal 1531mg/kg (1531mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 31(Suppl,
mouse LD50 intravenous 348mg/kg (348mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Chemotherapy Vol. 34(Suppl,
mouse LD50 oral 4526mg/kg (4526mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 31(Suppl,
mouse LD50 subcutaneous 2185mg/kg (2185mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 31(Suppl,
rat LD50 intramuscular 1680mg/kg (1680mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER Chemotherapy Vol. 34(Suppl,
rat LD50 intraperitoneal 1399mg/kg (1399mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 31(Suppl,
rat LD50 intravenous 326mg/kg (326mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Chemotherapy Vol. 34(Suppl,
rat LD50 oral 7936mg/kg (7936mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 31(Suppl,
rat LD50 subcutaneous 1398mg/kg (1398mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Chemotherapy Vol. 31(Suppl,

supplier list

Suntin MediPharma Co. Ltd.
Tel:+86 755 8386 5062 ; +852 2690 9351
Address: RM.2501-2502, 25/F., Convention & Exhibition Times Center, 3008 Yitian RD., Shenzhen China.
KOA SHOJI CO., LTD.
Tel:+81-45-540-6985
Address: 17-5, Minowa-cho, 2-chome, Kohoku-ku, Yokohama-shi, Kanagawa, 223-0051, Japan
Leawell International Limited
Tel:+852-(2576)-0298
Address: 18/F Catic Plaza, 8 Causeway Road Causeway Bay,
ACIC Fine Chemicals Inc.
Tel:+1-(800)-265-6727
Address: 11772 West Sample Road, Coral Springs, Florida 33065,
Tecoland Corporation
Tel:+1-(732)-603-9577
Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,
TaiZhou HiKong Chemical Co., Ltd.
Tel:+86-18967213045,13957694715
Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000,
Microchem
Tel:+86-(23)-86612540
Address: No.581, Nanping East Road, Nan An, Chong Qing 400060,
zhejiang hengdian import and export co., ltd
Tel:+86-571-87635726
Address: 3f, world trade center wtcz, 122shuguang rd, hangzhou, china
NINGBO PANGS CHEM INT'L CO.,LTD.
Tel:86-574-27666845
Address: FLOOR 21 BUILDING 11 XINTIANDI NO.689,SHIJIROAD,NINGBO,CHINA
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
Tel:86-27-59335372
Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
Nanjing Bangnuo Biotechnology Co., Ltd
Tel:86-1732-7098554
Address: shuanglong road,jiangning, nanjing,jiangsu
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Hebei Shuangchi Biological Technology Co.,Ltd
Tel:86-27-85442017
Address: Room 2109, Fu Xing Building, Xinhua Road, Jianghan District, Wuhan City, Hubei Province
Wuhan H.X.K Fine Chemicals Co.,LTD
Tel:86-27-59721024
Address: No. 139, hanyang Road, hubei city, Hubei Prov. China 434000

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