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3,3'-Dimethylbenzidine dihydrochloride (o-Tolidine dihydrochloride) cas no:612-82-8

Synonyms: Benzidine,3,3'-dimethyl-, dihydrochloride (8CI);[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethyl-,dihydrochloride (9CI);o-Tolidinedihydrochloride;

Identification
Name3,3'-Dimethylbenzidine dihydrochloride (o-Tolidine dihydrochloride)
CAS612-82-8
SynonymsBenzidine,3,3'-dimethyl-, dihydrochloride (8CI);[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dimethyl-,dihydrochloride (9CI);o-Tolidinedihydrochloride;
EINECS(EC#)210-322-5
Molecular FormulaC14H18Cl2N2
Molecular Weight212.29024
Chemical Properties
Appearancewhite to light yellow
storage tempDo not store in direct sunlight. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Sensitive Air Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T:Toxic;N:Dangerousfortheenvironment;
Risk R22;R45;R51/53;R68
Safety

Suspected carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Safety information of 3,3'-Dimethylbenzidine dihydrochloride (CAS NO.612-82-8):
Hazard Codes: T,N
Risk Statements:
45: May cause cancer
22: Harmful if swallowed
51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
68: Possible risk of irreversible effects
Safety Statements:
53: Avoid exposure - obtain special instruction before use
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
61: Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR: UN 3077 9/PG 3
WGK Germany: 3
RTECS: DD1226000
F: 3-8-9
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1.    

mma-sat 50 µg/plate

    CALEDQ    Cancer Letters (Shannon, Ireland). 4 (1977),21.
2.    

sln-dmg-orl 14 pph

    ENMUDM    Environmental Mutagenesis. 7 (1985),325.
3.    

sln-dmg-par 2750 ppm

    ENMUDM    Environmental Mutagenesis. 7 (1985),325.
4.    

orl-rat TDLo:1820 mg/kg/65W-C:CAR

    JACTDZ    Journal of the American College of Toxicology. 10 (2)(1991),255.
5.    

orl-mus TDLo:15,288 mg/kg/78W-C:CAR

    FCTOD7    Food and Chemical Toxicology. 27 (1989),801.
6.    

orl-rat TDLo:1120 mg/kg/14D-C

    NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-390 ,1991.
7.    

orl-rat TDLo:18,200 mg/kg/13W-C

    NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-390 ,1991.

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