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Benzenamine,N-methyl-N-nitroso- cas no:614-00-6

Synonyms: Aniline,N-methyl-N-nitroso- (6CI,8CI); Methylphenylnitrosamine;Methylphenylnitrosoamine; N-Methyl-N-nitrosoaniline; N-Methyl-N-phenylnitrosamine;N-Methyl-N-phenylnitrosoamine; N-Nitroso-N-methylaniline;N-Nitroso-N-methylphenylamine; N-methyl-N-nitrosobenzenamine; NSC 137;Nitrosomethylphenylamine; Phenylmethylnitrosamine

Identification
NameBenzenamine,N-methyl-N-nitroso-
CAS614-00-6
SynonymsAniline,N-methyl-N-nitroso- (6CI,8CI); Methylphenylnitrosamine;Methylphenylnitrosoamine; N-Methyl-N-nitrosoaniline; N-Methyl-N-phenylnitrosamine;N-Methyl-N-phenylnitrosoamine; N-Nitroso-N-methylaniline;N-Nitroso-N-methylphenylamine; N-methyl-N-nitrosobenzenamine; NSC 137;Nitrosomethylphenylamine; Phenylmethylnitrosamine
EINECS(EC#)210-366-5
Molecular FormulaC7H8 N2 O
Molecular Weight136.17
Chemical Properties
refractive index1.534
storage temp-20°C Freezer
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T
Risk 25-36-40-22-45
Safety

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Hazard Codes: ToxicT
Risk Statements: 25-36-40-22-45 
R22:Harmful if swallowed. 
R25 :Toxic if swallowed. 
R36:Irritating to eyes. 
R40:Limited evidence of a carcinogenic effect. 
R45:May cause cancer.
Safety Statements: 23-26-46-53-45 
S23:Do not breathe vapour. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S46:If swallowed, seek medical advice immediately and show this container or label. 
S53:Avoid exposure - obtain special instructions before use.


Toxicity
1.    

mma-sat 735 nmol/plate

    CALEDQ    Cancer Letters (Shannon, Ireland). 15 (1982),289.
2.    

mma-esc 50 nmol/plate

    GANNA2    Gann. Japanese Journal of Cancer Research. 75 (1984),8.
3.    

mrc-smc 2500 mg/L

    IAPUDO    IARC Publications. 57 (1984),721.
4.    

dni-mus-ipr 20 g/kg

    ARGEAR    Archiv fuer Geschwulstforschung. 51 (1981),605.
5.    

ipr-rat TDLo:140 mg/kg (9D preg):TER

    IARCCD    IARC Scientific Publications. 4 (1973),112.
6.    

orl-rat TDLo:61 mg/kg/29W-C:CAR

    CALEDQ    Cancer Letters (Shannon, Ireland). 1 (1976),215.
7.    

scu-rat TDLo:78 mg/kg/39W-I:CAR

    CALEDQ    Cancer Letters (Shannon, Ireland). 1 (1976),215.
8.    

orl-mus TDLo:2744 mg/kg/28W-C:NEO

    JNCIAM    Journal of the National Cancer Institute. 46 (1971),1029.
9.    

orl-rat TD:3400 mg/kg/35W-C:ETA

    ZEKBAI    Zeitschrift fuer Krebsforschung. 69 (1967),103.
10.    

orl-ham TDLo:1960 mg/kg/50W-I:ETA tumors

    CNREA8    Cancer Research. 48 (1988),6648.
11.   &

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