1,2-Phenylenediamine dihydrochloride cas no:615-28-1

Name1,2-Phenylenediamine dihydrochloride
CAS615-28-1
Synonyms1,2-Benzenediamine,dihydrochloride (9CI); o-Phenylenediamine, dihydrochloride (8CI);1,2-Diaminobenzene dihydrochloride; 1,2-Phenylenediamine dihydrochloride
EINECS(EC#)210-418-7
Molecular FormulaC6H8 N2 . 2 Cl H
Molecular Weight108.14112

storage temp2-8°C

Hazardclass6.1(b)

Hazard Xn,N,T
Risk 22-40-43-51/53-68-50/53-36-25-20/21-36/37/38
Safety

Poison by intraperitoneal route. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NO_x. See also m-PHENYLENEDIAMINE; o-PHENYLENEDIAMINE; p-PHENYLENEDIAMINE; p-PHENYLENEDIAMINE DIHYDROCHLORIDE; m-PHENYLENEDIAMINE HYDROCHLORIDE; p-PHENYLENEDIAMINESULFONIC ACID; 1,3-PHENYLENEDIAMINE-4-SULFONIC ACID and AMINES.
 

Hazard Codes: XnNT
Risk Statements: 22-40-43-51/53-68-50/53-36-25-20/21-36/37/38 
R20/21:Harmful by inhalation and in contact with skin. 
R22:Harmful if swallowed. 
R25 :Toxic if swallowed. 
R36:Irritating to eyes. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R40:Limited evidence of a carcinogenic effect. 
R43:May cause sensitization by skin contact. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R68:Possible risk of irreversible effects.
Safety Statements: 36/37-61-60-45-28-26 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	subcutaneous	4gm/kg (4000mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930.
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)		National Technical Information Service. Vol. AD414-344,
mouse	LDLo	subcutaneous	250mg/kg (250mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930.
rabbit	LD	subcutaneous	> 500mg/kg (500mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930.
rat	LD50	intraperitoneal	290mg/kg (290mg/kg)		Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institut by Bio-Research Consultants, Inc. Vol. NCI-E-68-1311, Pg. 1973,
rat	LDLo	subcutaneous	600mg/kg (600mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 140, 1930.