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Carbamic acid,N-methyl-N-nitroso-, ethyl ester cas no:615-53-2

Synonyms: Carbamicacid, methylnitroso-, ethyl ester (6CI,8CI,9CI); EthylN-methylnitrosocarbamate; Methylnitrosourethane; N-Methyl-N-nitrosourethane;N-Nitroso-N-methylurethane; NMU; NSC 2860; Nitrosomethylurethane

Identification
NameCarbamic acid,N-methyl-N-nitroso-, ethyl ester
CAS615-53-2
SynonymsCarbamicacid, methylnitroso-, ethyl ester (6CI,8CI,9CI); EthylN-methylnitrosocarbamate; Methylnitrosourethane; N-Methyl-N-nitrosourethane;N-Nitroso-N-methylurethane; NMU; NSC 2860; Nitrosomethylurethane
EINECS(EC#)210-432-3
Molecular FormulaC4H8 N2 O3
Molecular Weight132.14
Chemical Properties
refractive index1.462
storage tempRefrigerator
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass1.1A
Safety Data

Safety

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by inhalation. Experimental reproductive effects. Mutation data reported. Has been implicated as a transplacental brain carcinogen. Combustible when exposed to heat, sparks, open flame, and powerful oxidizers. Explodes when heated. A storage hazard. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES and CARBAMATES.

Risk Statements 5-36/37/38-40
R5 : Heating may cause an explosion. 
R36/37/38: Irritating to eyes, respiratory system and skin. 
R40: Limited evidence of a carcinogenic effect.
Safety Statements 23-35-45-53
S23: Do not breathe vapour. 
S35: This material and its container must be disposed of in a safe way. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53: Avoid exposure - obtain special instructions before use.
RIDADR: 2810
RTECS: FC6300000
HazardClass: 1.1A
PackingGroup: I


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
hamster LDLo subcutaneous 21mg/kg (21mg/kg)   American Journal of Pathology. Vol. 50, Pg. 639, 1967.
mammal (species unspecified) LD50 intravenous 4mg/kg (4mg/kg)   Gann Monograph on Cancer Research. Vol. 17, Pg. 107, 1975.
mammal (species unspecified) LD50 oral 240mg/kg (240mg/kg)   Gann Monograph on Cancer Research. Vol. 17, Pg. 107, 1975.
mouse LCLo inhalation 600mg/m3/10M (600mg/m3)   National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. MAR1942,
mouse LD50 intraperitoneal 37mg/kg (37mg/kg)   Cancer Research. Vol. 30, Pg. 11, 1970.
mouse LDLo subcutaneous 7mg/kg (7mg/kg)   British Journal of Cancer. Vol. 23, Pg. 167, 1969.
rat LD50 intravenous 4mg/kg (4mg/kg)   Zeitschrift fuer Krebsforschung. Vol. 69, Pg. 103, 1967.
rat LD50 oral 180mg/kg (180mg/kg)   Naturwissenschaften. Vol. 48, Pg. 165, 1961.
rat LDLo intraperitoneal 50mg/kg (50mg/kg)   British Journal of Cancer. Vol. 22, Pg. 316, 1968.
rat LDLo subcutaneous 125mg/kg (125mg/kg)   British Journal of Cancer. Vol. 16, Pg. 92, 1962.

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