5-Hepten-2-amine,N,6-dimethyl-, hydrochloride (1:1) cas no:6168-86-1

Name5-Hepten-2-amine,N,6-dimethyl-, hydrochloride (1:1)
CAS6168-86-1
Synonyms4-Hexenylamine,N,1,5-trimethyl-, hydrochloride (6CI,8CI); 5-Hepten-2-amine, N,6-dimethyl-,hydrochloride (9CI); Isometheptene hydrochloride; NSC 13066
EINECS(EC#)228-211-5
Molecular FormulaC9H19 N . Cl H
Molecular Weight177.75

Safety

Poison by intraperitoneal, intravenous, parenteral, and subcutaneous routes. An adrenergic agent. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	26mg/kg (26mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 92, Pg. 214, 1948.
dog	LD50	subcutaneous	76mg/kg (76mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 92, Pg. 214, 1948.
frog	LDLo	parenteral	200mg/kg (200mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Quarterly Journal of Pharmacy & Pharmacology. Vol. 9, Pg. 647, 1936.
mouse	LD50	intravenous	18mg/kg (18mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Pharmacology and Experimental Therapeutics. Vol. 92, Pg. 214, 1948.
mouse	LD50	subcutaneous	171mg/kg (171mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 92, Pg. 214, 1948.
rabbit	LD50	intravenous	18mg/kg (18mg/kg)	BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Journal of Pharmacology and Experimental Therapeutics. Vol. 92, Pg. 214, 1948.
rabbit	LD50	subcutaneous	101mg/kg (101mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 92, Pg. 214, 1948.
rat	LD50	intraperitoneal	70mg/kg (70mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 235, 1944.
rat	LDLo	subcutaneous	160mg/kg (160mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 71, Pg. 62, 1941.