Phenacetin cas no:62-44-2
Synonyms: 1-acetamido-4-ethoxybenzene; para-Acetophenetidide; p-acetophenetidine; p-acetophenetide; p-acetphenetidin; paracetophentidin; p-Ethoxyacetanilide; 4'-ethoxyacetanilide; Para-phenacetin; acet-p-phenalide; acet-p-phenetidin; aceto-para-phenalide; aceto-para-phenetidide; Acetophenetidine; acetophenetin; acetylphenetidin; coricidin; empirin compound; N-(4-ethoxyphenyl)-acetamide; N-Acetyl-4-ethoxyaniline; N-acetyl-p-phenetidine; phenacet; phenazetin; Phorazetim; pyraphen;
NamePhenacetin
CAS62-44-2
Synonyms1-acetamido-4-ethoxybenzene; para-Acetophenetidide; p-acetophenetidine; p-acetophenetide; p-acetphenetidin; paracetophentidin; p-Ethoxyacetanilide; 4'-ethoxyacetanilide; Para-phenacetin; acet-p-phenalide; acet-p-phenetidin; aceto-para-phenalide; aceto-para-phenetidide; Acetophenetidine; acetophenetin; acetylphenetidin; coricidin; empirin compound; N-(4-ethoxyphenyl)-acetamide; N-Acetyl-4-ethoxyaniline; N-acetyl-p-phenetidine; phenacet; phenazetin; Phorazetim; pyraphen;
EINECS(EC#)200-533-0
Molecular FormulaC10H13NO2
Molecular Weight179.22
Appearancewhite crystalline powder
refractive index1.505 (20 C)
storage temp2-8°C
Sensitive Hygroscopic
Hazard T:Toxic
Risk R22;R45
Safety
Confirmed carcinogen producing tumors of the kidney and bladder. A human poison by an unspecified route. Poison by intravenous and possibly other routes. Moderately toxic by several routes. Human systemic effects by ingestion: cyanosis, liver damage, and methemoglobinemia-carboxyhemoglobinemia. Experimental teratogenic data. Other experimental reproductive effects. Mutation data reported. Chronic effects consist of weight loss, insomnia, shortness of breath, weakness, and often aplastic anemia. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:?T
Risk Statements: 45-22-20/21/22?
R45:May cause cancer.?
R22:Harmful if swallowed.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 53-45?
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: AM4375000
Hazardous Substances Data: 62-44-2(Hazardous Substances Data)
| 1. |
??? |
mma-sat:333?μg/plate
|
??? |
IARCCD ?? IARC Scientific Publications. 27 (1980),283. |
| 2. |
??? |
sce-mus-ipr 165?mg/kg
|
??? |
JTEHD6 ?? Journal of Toxicology and Environmental Health. 16 (1985),355. |
| 3. |
??? |
unr-man LDLo:74?mg/kg
|
??? |
85DCAI ?? Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73. |
| 4. |
??? |
orl-rat LD50:3600?mg/kg
|
??? |
ARZNAD ?? Arzneimittel-Forschung. Drug Research. 24 (1974),600. |
| 5. |
??? |
ipr-rat LD50:634?mg/kg
|
??? |
NYKZAU ?? Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 62 (1966),11. |
| 6. |
??? |
orl-mus LD50:866?mg/kg
|
??? |
ARZNAD ?? Arzneimittel-Forschung. Drug Research. 28 (1978),1644. |
| 7. |
??? |
ihl-mus LC50:33,900?mg/m3
|
??? |
GISAAA ?? Gigiena i Sanitariya. 34 (10)(1969),36. |
| 8. |
??? |
ipr-mus LD50:540?mg/kg
|
??? |
YKKZAJ ?? Yakugaku Zasshi. Journal of Pharmacy. 81 (1961),659. |
| 9. |
??? |
scu-mus LD50:1625?mg/kg
|
??? |
ARZNAD ?? Arzneimittel-Forschung. Drug Research. 8 (1958),25. |
| 10. |
??? |
ivn-dog LDLo:260?mg/kg
|
??? |
NTIS** ?? National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technica |
?Acetamide,N-(4-ethoxyphenyl)- (CAS NO.62-44-2) hasn't been listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
