62-46-4|Lipoic acidProducts Supply - Chemical intermediates Network

Lipoic acid cas no:62-46-4

Synonyms: 1,2-Dithiolane-3-pentanoic acid; 5-(1,2-Dithiolan-3-yl)valeric acid

Identification

NameLipoic acid
CAS62-46-4
Synonyms1,2-Dithiolane-3-pentanoic acid; 5-(1,2-Dithiolan-3-yl)valeric acid
EINECS(EC#)200-534-6
Molecular FormulaC8H14O2S2
Molecular Weight206.32

Safety Data

Safety

WGK Germany of Lipoic acid (CAS NO.62-46-4): 3
Since the early 1990s lipoic acid has been consumed as a dietary supplement, typical doses are 100–200 mg/day. A chronic/carcinogenicity study in rats reported that racemic lipoic acid was found to be non-carcinogenic and did not show any evidence of target organ toxicity. The NOAEL is considered to be 60 mg/kg bw/day.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	160mg/kg (160mg/kg)	?	Drugs in Japan Vol. 6, Pg. 454, 1982.
mouse	LD50	intravenous	197mg/kg (197mg/kg)	?	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 60, Pg. 278, 1964.
mouse	LD50	oral	502mg/kg (502mg/kg)	?	Archives of Toxicology. Vol. 41, Pg. 79, 1978.
mouse	LD50	subcutaneous	200mg/kg (200mg/kg)	?	Drugs in Japan Vol. 6, Pg. 454, 1982.
rat	LD50	intraperitoneal	200mg/kg (200mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 68, Pg. 265, 1972.
rat	LD50	intravenous	180mg/kg (180mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 68, Pg. 265, 1972.
rat	LD50	oral	1130mg/kg (1130mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 68, Pg. 265, 1972.
rat	LD50	subcutaneous	230mg/kg (230mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 68, Pg. 265, 1972.

supplier list

Nanjing Phyto-Spring Imp. & Exp. Co., Ltd.: Tel:+86-(25)-8324-3292, 8324-7202; Address: 68 Shan Xi Road, Suite 10-I# Yi-He Mansion, NanJing, Jiangsu,

Suzhou Yuanfang Chemical Co., Ltd.: Tel:+86-(512)-53413633,53414911; Address: FuHao Developing zone, TaiCang, JiangSu 215400,

Beckmann-Kenko GmbH: Tel:+49-(4241)-9308-88; Address: Auf Dem Scheunenbrink 8, Bassum D-27211,

Aceto Corporation: Tel:+1-(516)-627-6000; Address: One Hallow Lane, Lake Success, New York 11042-1215,

Austin Chemical Company, Inc.: Tel:+1-(847)-520 9600; Address: 1565 Barclay Blvd., Buffalo Grove, Illinois 60089,

Asiamerica Ingredients, Inc.: Tel:+1-(201)-497-5993; Address: 245 Old Hook Road, Westwood, New Jersey 7675,

Creative Compounds, LLC: Tel:+1-(877)-203-6010; Address: 600 Daugherty, Scott City, Missouri 63780,

Chinese Biochemicals Sourcing: Tel:+86-(551)-5329876; Address: Building E, Information Industrial Base, No.11 Tianzhu Road, Hefei, Anhui 230088,

Ningbo Pangs Chem Int'l Co. Ltd.: Tel:+86-(574)-27668808; Address: Floor 21, Building 11, Xintiandi, No. 689, Shiji Road, Ningbo 315040,

Vitajoy Bio-tech Co., Ltd: Tel:+86-(512)-68278318; Address: 19A, No.1298,SANXIANG ROAD, SUZHOU CITY 215004,

Depew Fine Chemicals Co., Ltd: Tel:+86-(571)-87630650, 87630656; Address: Room 202, No.317 Wantang Road, Hangzhou 310007,

Shanghai Biochemical Co., Ltd.: Tel:+86-(21)-50921947; Address: 13-402, Lane 1260 East Huaxia Rd, Shanghai 201200,

UNIBEST Biopharma (Shanghai) CO., LTD.: Tel:; Address: 5/F, ChuangShiDai Mansion BaiZhang DongLu, 852 315040, NINGBO

Taizhou P&J International Trade Co., Ltd.: Tel:+86-(576)-86137488, 86137955; Address: 901 Room, Xingyuan Mansion, Wenling, Zhejiang 317500,

Nanjing Da Bang Pharma & Chem Co., Ltd.: Tel:+86-(25)-83197856; Address: 1503 Huijie Plaza. 268# Zhongshan Road, Nanjing, Jiangsu 210008,

Lipoic acid cas no:62-46-4

Directory

supplier list