1-Propanaminium,2-(acetyloxy)-N,N,N-trimethyl-, chloride (1:1) cas no:62-51-1
Synonyms: (2-Hydroxypropyl)trimethylammoniumchloride acetate (6CI); 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-,chloride (9CI); Ammonium, (2-hydroxypropyl)trimethyl-, chloride, acetate (8CI);(2-Acetoxypropyl)trimethylammonium chloride; (?à)-Acetyl-b-methylcholine chloride; Acetyl-b-methylcholine chloride; Amechol; DL-Acetyl-b-methylcholine chloride; Mecholinechloride; Mecholyl; Methacholine chloride; Methacholinium chloride; O-Acetyl-b-methylcholine chloride;Provocholine; Trimethyl-b-acetoxypropylammonium chloride; b-Methylacetylcholine chloride
Name1-Propanaminium,2-(acetyloxy)-N,N,N-trimethyl-, chloride (1:1)
CAS62-51-1
Synonyms(2-Hydroxypropyl)trimethylammoniumchloride acetate (6CI); 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-,chloride (9CI); Ammonium, (2-hydroxypropyl)trimethyl-, chloride, acetate (8CI);(2-Acetoxypropyl)trimethylammonium chloride; (?à)-Acetyl-b-methylcholine chloride; Acetyl-b-methylcholine chloride; Amechol; DL-Acetyl-b-methylcholine chloride; Mecholinechloride; Mecholyl; Methacholine chloride; Methacholinium chloride; O-Acetyl-b-methylcholine chloride;Provocholine; Trimethyl-b-acetoxypropylammonium chloride; b-Methylacetylcholine chloride
EINECS(EC#)200-537-2
Molecular FormulaC8H18 N O2 . Cl
Molecular Weight195.68702
AppearanceWhite hygroscopic crystals with slight odor of dead fish.
storage temp2-8°C
Hazard Xn: Harmful;
Risk R22
Safety
Safety Information of 0-acetyl-β-methylcholine chloride viki (62-51-1):
Hazard Codes: Xn.gif)
Risk Statements: 22-36/37/38
22: Harmful if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements: 26-36
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by other routes. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| guinea pig |
LDLo |
intravenous |
3750ug/kg (3.75mg/kg) |
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 245, 1956. |
| mouse |
LD50 |
intraperitoneal |
160mg/kg (160mg/kg) |
|
Toxicology and Applied Pharmacology. Vol. 28, Pg. 227, 1974. |
| mouse |
LD50 |
intravenous |
15mg/kg (15mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 337, 1936. |
| mouse |
LD50 |
oral |
740mg/kg (740mg/kg) |
|
Pharmacology and Toxicology. English translation of FATOAO. Vol. 22, Pg. 210, 1959. |
| mouse |
LD50 |
subcutaneous |
90mg/kg (90mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 337, 1936. |
| rat |
LD50 |
intravenous |
20mg/kg (20mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 337, 1936. |
| rat |
LD50 |
oral |
750mg/kg (750mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 337, 1936. |
| rat |
LD50 |
subcutaneous |
75mg/kg (75mg/kg) |
|
Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 337, 1936. |
