Cevane-3,4,12,14,16,17,20-heptol,4,9-epoxy-, 3-[(2Z)-2-methyl-2-butenoate], (3b,4a,16b)- cas no:62-59-9

Synonyms: Cevadine(6CI,7CI); Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-,3-(2-methyl-2-butenoate), [3b(Z),4a,16b]-; Cevane-3b,4b,12,14,16b,17,20-heptol, 4,9-epoxy-, 3-(2-methylcrotonate), (Z)-(8CI); 2H-4,16a-Epoxybenzo[7,8]fluoreno[2,1-b]quinolizine,cevane-3,4,12,14,16,17,20-heptol deriv.; Cevadin; NSC 93767; Veratrine;Veratrine (crystallized)

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Identification
Chemical Properties
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Safety Data
Toxicity

Identification

NameCevane-3,4,12,14,16,17,20-heptol,4,9-epoxy-, 3-[(2Z)-2-methyl-2-butenoate], (3b,4a,16b)-
CAS62-59-9
SynonymsCevadine(6CI,7CI); Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-,3-(2-methyl-2-butenoate), [3b(Z),4a,16b]-; Cevane-3b,4b,12,14,16b,17,20-heptol, 4,9-epoxy-, 3-(2-methylcrotonate), (Z)-(8CI); 2H-4,16a-Epoxybenzo[7,8]fluoreno[2,1-b]quinolizine,cevane-3,4,12,14,16,17,20-heptol deriv.; Cevadin; NSC 93767; Veratrine;Veratrine (crystallized)
EINECS(EC#)200-545-6
Molecular FormulaC32H49 N O9
Molecular Weight591.82

Chemical Properties

refractive index1.647

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(a)

Safety Data

Safety

Safety Information of Cevadine (CAS NO. 62-59-9):
RIDADR: 1544
HazardClass: 6.1(a)
PackingGroup: II
Poison by intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

1.	ipr-mus LD50:3500 µg/kg	PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 76 (1951),847.
2.	scu-mus LD50:4900 µg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 113 (1955),89.
3.	ivn-mus LD50:1 mg/kg	PHREA7 Physiological Reviews. 26 (1946),383.
4.	scu-gpg LDLo:1 mg/kg	PHREA7 Physiological Reviews. 26 (1946),383.

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