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Benzeneacetic acid, a-phenyl-a-propyl-, 2-(diethylamino)ethylester, hydrochloride (1:1) cas no:62-68-0

Synonyms: Benzeneaceticacid, a-phenyl-a-propyl-, 2-(diethylamino)ethylester, hydrochloride (9CI); Valeric acid, 2,2-diphenyl-, 2-(diethylamino)ethylester hydrochloride (6CI,8CI); 2-(Diethylamino)ethyl 2,2-diphenylvaleratehydrochloride; 2'-Diethylaminoethyl 2,2-diphenylpentanoate hydrochloride;Proadifen hydrochloride; RP 5171; SKF 525; SKF 525A; U 5446; b-Diethylaminoethyldiphenylpropylacetate hydrochloride

Identification
NameBenzeneacetic acid, a-phenyl-a-propyl-, 2-(diethylamino)ethylester, hydrochloride (1:1)
CAS62-68-0
SynonymsBenzeneaceticacid, a-phenyl-a-propyl-, 2-(diethylamino)ethylester, hydrochloride (9CI); Valeric acid, 2,2-diphenyl-, 2-(diethylamino)ethylester hydrochloride (6CI,8CI); 2-(Diethylamino)ethyl 2,2-diphenylvaleratehydrochloride; 2'-Diethylaminoethyl 2,2-diphenylpentanoate hydrochloride;Proadifen hydrochloride; RP 5171; SKF 525; SKF 525A; U 5446; b-Diethylaminoethyldiphenylpropylacetate hydrochloride
Molecular FormulaC23H31 N O2 . Cl H
Molecular Weight390.01
Chemical Properties
storage temp−20°C
Safety Data

Hazard Xn
Risk 22
Safety

Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. Experimental reproductive effects. See also ESTERS. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Hazard Codes of Proadifen hydrochloride (CAS NO.62-68-0): HarmfulXn
Risk Statements: 22 
R22:Harmful if swallowed.
Safety Statements: 36 
S36:Wear suitable protective clothing.


Toxicity
1.    

scu-rat TDLo:20 mg/kg (female 4D pre):REP

    JSICAZ    Journal of Scientific and Industrial Research, Section C: Biological Sciences. 19 (1960),264.
2.    

orl-rat LD50:2140 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,366.
3.    

ipr-rat LD50:163 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,366.
4.    

orl-mus LD50:538 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,366.
5.    

ipr-mus LD50:110 mg/kg

    PCJOAU    Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 3 (1969),508.
6.    

scu-mus LD50:90 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 98 (1950),121.
7.    

ivn-mus LD50:60 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,366.
8.    

ivn-cat LDLo:25 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),118.

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