HYOSCYAMINE SULFATE cas no:620-61-1

Safety Risk Statements:26/28
26/28:Very Toxic by inhalation and if swallowed
Safety Statements:1-24/25-45
1:Keep locked up
24/25:Avoid contact with skin and eyes
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

YM6107000

CAS REGISTRY NUMBER :

620-61-1

LAST UPDATED :

199712

DATA ITEMS CITED :

7

MOLECULAR FORMULA :

C34-H46-N2-O6.H2-O4-S

MOLECULAR WEIGHT :

676.90

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - infant

DOSE/DURATION :

400 uL/kg/1D-I

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Cardiac - pulse rate increase, without fall in BP Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :

AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 15,532,1997

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - infant

DOSE/DURATION :

800 uL/kg/1D-I

TOXIC EFFECTS :

Behavioral - irritability Cardiac - pulse rate increase, without fall in BP Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :

AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 15,532,1997

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - infant

DOSE/DURATION :

400 uL/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Cardiac - pulse rate increase, without fall in BP Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :

AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 15,532,1997

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

210 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 55,849,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80431 No. of Facilities: 967 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 3990 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80431 No. of Facilities: 445 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 14970 (estimated) No. of Female Employees: 12609 (estimated)