2-chloro-1,4-benzenediamine sulfate cas no:6219-71-2

Hazard Xn: Harmful;
Risk 20/21-36/37/38
Safety

Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of Cl⁻, SO_x, and NO_x. See also AROMATIC AMINES and SULFATES.
Safety Information about 2-Chlorobenzene-1,4-diamine; sulfuric acid (CAS NO.6219-71-2):
Hazard Codes: 
Xn:
Risk Statements about 2-Chlorobenzene-1,4-diamine; sulfuric acid (CAS NO.6219-71-2):
R20/21: Harmful by inhalation and in contact with skin.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about 2-Chlorobenzene-1,4-diamine; sulfuric acid (CAS NO.6219-71-2):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 3
RTECS: CZ1581000

CHEMICAL IDENTIFICATION

RTECS NUMBER :

SS9000000

CHEMICAL NAME :

p-Phenylenediamine, 2-chloro-, sulfate

CAS REGISTRY NUMBER :

6219-71-2

LAST UPDATED :

199701

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C6-H5-Cl-N2.xH2-O4-S

MOLECULAR WEIGHT :

827.14

WISWESSER LINE NOTATION :

ZR DZ BG &..H2.S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

41 gm/kg/77W-C

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Liver - tumors

REFERENCE :

CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 1,495,1980

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

194 gm/kg/77W-C

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

REFERENCE :

CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 1,495,1980

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

12150 gm/kg/96W-C

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

REFERENCE :

CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 1,495,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2756 No. of Facilities: 626 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 5537 (estimated) No. of Female Employees: 2853 (estimated)