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2(1H)-Quinolinone,8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-, hydrochloride(1:1), rel- cas no:62929-91-3

Synonyms: 2(1H)-Quinolinone,8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-,monohydrochloride, rel- (9CI); 2(1H)-Quinolinone,8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride,(R*,S*)-(?à)-; 2(1H)-Quinolinone,8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride,(R*,S*)-; Meptin; OPC 2009; Procaterol hydrochloride

Identification
Name2(1H)-Quinolinone,8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-, hydrochloride(1:1), rel-
CAS62929-91-3
Synonyms2(1H)-Quinolinone,8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-,monohydrochloride, rel- (9CI); 2(1H)-Quinolinone,8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride,(R*,S*)-(?à)-; 2(1H)-Quinolinone,8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride,(R*,S*)-; Meptin; OPC 2009; Procaterol hydrochloride
EINECS(EC#)263-763-0
Molecular FormulaC16H22 N2 O3 . Cl H
Molecular Weight326.86
Chemical Properties
storage temp2-8°C
Safety Data

Safety

RTECS: VC8296000
Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 100mg/kg (100mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.
dog LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.
mouse LD50 intraperitoneal 330mg/kg (330mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.
mouse LD50 intravenous 70300ug/kg (70.3mg/kg)   United States Patent Document. Vol. #4579854,
mouse LD50 oral 3200mg/kg (3200mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.
mouse LD50 subcutaneous 370mg/kg (370mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.
rabbit LD50 intravenous 83mg/kg (83mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.
rabbit LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.
rat LD50 intraperitoneal 487mg/kg (487mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 22, Pg. 191, 1981.
rat LD50 intravenous 80mg/kg (80mg/kg)   United States Patent Document. Vol. #4026897,
rat LD50 oral 2600mg/kg (2600mg/kg)   United States Patent Document. Vol. #4026897,
rat LD50 subcutaneous 900mg/kg (900mg/kg)   Drugs in Japan Vol. 6, Pg. 719, 1982.

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