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Methanone,4-morpholinyl(3,4,5-trimethoxyphenyl)- cas no:635-41-6

Synonyms: Morpholine,4-(3,4,5-trimethoxybenzoyl)- (6CI,7CI,8CI,9CI);4-(3,4,5-Trimethoxybenzoyl)morpholine; 4-(3,4,5-Trimethoxybenzoyl)tetrahydro-1,4-oxazine;Abbott 22370; N-(3,4,5-Trimethoxybenzoyl)tetrahydro-1,4-oxazine; NSC 62939;Opalene; PS 2383; Sedoxazine; Trifenoxazin; Trimethoxazine; Trimetozin;Trimetozine; Trioxazin; Trioxazine; V 7

Identification
NameMethanone,4-morpholinyl(3,4,5-trimethoxyphenyl)-
CAS635-41-6
SynonymsMorpholine,4-(3,4,5-trimethoxybenzoyl)- (6CI,7CI,8CI,9CI);4-(3,4,5-Trimethoxybenzoyl)morpholine; 4-(3,4,5-Trimethoxybenzoyl)tetrahydro-1,4-oxazine;Abbott 22370; N-(3,4,5-Trimethoxybenzoyl)tetrahydro-1,4-oxazine; NSC 62939;Opalene; PS 2383; Sedoxazine; Trifenoxazin; Trimethoxazine; Trimetozin;Trimetozine; Trioxazin; Trioxazine; V 7
EINECS(EC#)211-236-0
Molecular FormulaC14H19 N O5
Molecular Weight281.34
Chemical Properties
refractive index1.529
Safety Data

Safety

Moderately toxic by ingestion, intraperitoneal, subcutaneous, parenteral, and intravenous routes. An experimental teratogen. Experimental reproductive effects. When Trimethoxazine (CAS NO.635-41-6) is heated to decomposition, it emits toxic fumes of NOx.


Toxicity
1.    

orl-rat LD50:1800 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 21 (1971),719.
2.    

ipr-rat LD50:1080 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
3.    

scu-rat LD50:1400 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
4.    

orl-mus LD50:2400 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
5.    

ipr-mus LD50:1150 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 4 (1976),2487.
6.    

scu-mus LD50:1550 mg/kg

    THERAP    Therapie. 20 (1965),401.
7.    

ivn-mus LD50:960 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,312.
8.    

par-mus LD50:1200 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 33 (1970),70.

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