Phenylarsine oxide cas no:637-03-6

NamePhenylarsine oxide
CAS637-03-6
SynonymsOxophenylarsine; phenylarsine oxide, mixture of oligomers; Phenylarsine oxide solution
EINECS(EC#)211-275-3
Molecular FormulaC6H5AsO
Molecular Weight168.02

storage tempPoison room

Hazardclass6.1

Hazard T:Toxic;N:Dangerousfortheenvironment;
Risk R23/25;R50/53
Safety

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of As. See also ARSENIC COMPOUNDS.
Hazard CodesT,N
Risk Statements 23/25-50/53
R23/25:Toxic by inhalation and if swallowed. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements 20/21-28-45-60-61
S20/21: When using, do not eat, drink or smoke
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR UN 3465 6.1/PG 3
WGK Germany 3
RTECS CH8100000
HazardClass 6.1
PackingGroup III

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1930ug/kg (1.93mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 74, Pg. 210, 1942.
mouse	LD50	unreported	1900ug/kg (1.9mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 70, Pg. 221, 1940.
mouse	LDLo	intravenous	1570ug/kg (1.57mg/kg)		Pharmaceutical Bulletin. Vol. 2, Pg. 19, 1954.
rabbit	LD50	intravenous	790ug/kg (0.79mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 69, Pg. 342, 1940.