D-Gluconamide,N,N'-[2,4,6-triiodo-5-[(methylamino)carbonyl]-1,3-phenylene]bis- cas no:63941-74-2

NameD-Gluconamide,N,N'-[2,4,6-triiodo-5-[(methylamino)carbonyl]-1,3-phenylene]bis-
CAS63941-74-2
Synonyms3,5-Bisgluconamido-2,4,6-triiodo-N-methylbenzamide;Ioglucomide; MP 8000; MP 8000 (pharmaceutical)
Molecular FormulaC20H28 I3 N3 O13
Molecular Weight899.21

refractive index1.8

Safety

Poison by intracerebral route. When heated to decomposition it emits toxic fumes of I⁻ and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	22700mg/kg (22700mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: ANTICONVULSANT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Radiology. Vol. 140, Pg. 713, 1981.
mouse	LD50	intravenous	16200mg/kg (16200mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: ANTICONVULSANT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Radiology. Vol. 140, Pg. 713, 1981.
rabbit	LD50	intravenous	23800mg/kg (23800mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: ANTICONVULSANT BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Radiology. Vol. 140, Pg. 713, 1981.
rat	LD50	intracrebral	365mg/kg (365mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: ANTICONVULSANT BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Radiology. Vol. 140, Pg. 713, 1981.
rat	LD50	intravenous	15600mg/kg (15600mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Radiology. Vol. 140, Pg. 713, 1981.