2,6-Piperidinedione,4-ethyl-4-methyl- cas no:64-65-3

Name2,6-Piperidinedione,4-ethyl-4-methyl-
CAS64-65-3
SynonymsGlutarimide,3-ethyl-3-methyl- (8CI); 2,6-Dioxo-4-methyl-4-ethylpiperidine;3-Ethyl-3-methylglutarimide; 3-Methyl-3-ethylglutarimide;4-Ethyl-4-methyl-2,6-dioxopiperidine; 4-Ethyl-4-methyl-2,6-piperidinedione;4-Methyl-4-ethyl-2,6-dioxopiperidine; Agipnon; Ahypnon; Antibarbi; Bemegrid;Bemegride; Etimid; Eukraton; Malysol; Megibal; Megimid; Megimide;Methetharimide; Mikedimide; NP 13; NSC 168667; NSC 58187; Zentraleptin; b-Ethyl-b-methylglutarimide; b-Methyl-b-ethylglutarimide
EINECS(EC#)200-588-0
Molecular FormulaC8H13 N O2
Molecular Weight155.22

refractive index1.448
storage temp−20°C

Hazardclass6.1(a)

Hazard T
Risk R23/24/25
Safety

Poison by ingestion, intravenous, intraperitoneal, intramuscular, subcutaneous, and parenteral routes. Human systemic effects by ingestion: wakefulness, hallucinations, distorted perceptions, toxic psychosis. An analeptic, central nervous system stimulant; used to counteract barbiturate poisoning. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: T
Risk Statements: 23/24/25
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed
Safety Statements: 22-36/37/39-45 
S22:Do not breathe dust 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible)
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: MA4550000
HazardClass: 6.1(a)
PackingGroup: II

1.		orl-wmn TDLo:100 mg/kg:CNS		LANCAO    Lancet. 2 (1956),967.
2.		orl-man TDLo:20 mg/kg:CNS		LANCAO    Lancet. 2 (1956),967.
3.		ipr-rat LD50:24 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),9.
4.		scu-rat LD50:31 mg/kg		JPPMAB    Journal of Pharmacy and Pharmacology. 13 (1961),244.
5.		ivn-rat LD50:16 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),9.
6.		orl-mus LD50:41 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
7.		ipr-mus LD50:25 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
8.		scu-mus LD50:27 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
9.		ivn-mus LD50:16 mg/kg		AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),9.
10.		ims-mus LD50:33 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutic