64-77-7|Benzenesulfonamide,N-[(butylamino)carbonyl]-4-methyl-Products Supply

Benzenesulfonamide,N-[(butylamino)carbonyl]-4-methyl- cas no:64-77-7

Synonyms: Urea,1-butyl-3-(p-tolylsulfonyl)- (8CI);1-Butyl-3-(p-methylphenylsulfonyl)urea;1-Butyl-3-(p-tolylsulfonyl)urea;3-(p-Tolyl-4-sulfonyl)-1-butylurea;Aglicid;Arkozal;Artosin;Artozin;Butamid;Butamide;D 860;Diaben;Diabetamid;Diabetol;Diabuton;Diasulfon;Dolipol;Glyconon;HLS 831;Ipoglicone;Mobenol;N-(4-Methylbenzenesulfonyl)-N'-butylurea;N-(4-Methylphenylsulfonyl)-N'-butylurea;N-(Sulfonyl-p-methylbenzene)-N'-n-butylurea;N-(p-Methylbenzenesulfonyl)-N'-butylurea;N-(p-Tolylsulfonyl)-N'-butylcarbamide;N-Butyl-N'-(4-methylphenylsulfonyl)urea;N-Butyl-N'-(p-tolylsulfonyl)urea;N-Butyl-N'-p-toluenesulfonylurea;N-n-Butyl-N'-tosylurea;NSC 23813;NSC 87833;Orabet;Oralin;Orezan;Orinase;Orinaz;Oterben;Pramidex;Rastinon;Tolbusal;Tolbutamid;Tolbutamide;Toluina;Tolumid;Tolumide;Toluvan;U 2043;Willbutamide;

Identification

NameBenzenesulfonamide,N-[(butylamino)carbonyl]-4-methyl-
CAS64-77-7
SynonymsUrea,1-butyl-3-(p-tolylsulfonyl)- (8CI);1-Butyl-3-(p-methylphenylsulfonyl)urea;1-Butyl-3-(p-tolylsulfonyl)urea;3-(p-Tolyl-4-sulfonyl)-1-butylurea;Aglicid;Arkozal;Artosin;Artozin;Butamid;Butamide;D 860;Diaben;Diabetamid;Diabetol;Diabuton;Diasulfon;Dolipol;Glyconon;HLS 831;Ipoglicone;Mobenol;N-(4-Methylbenzenesulfonyl)-N'-butylurea;N-(4-Methylphenylsulfonyl)-N'-butylurea;N-(Sulfonyl-p-methylbenzene)-N'-n-butylurea;N-(p-Methylbenzenesulfonyl)-N'-butylurea;N-(p-Tolylsulfonyl)-N'-butylcarbamide;N-Butyl-N'-(4-methylphenylsulfonyl)urea;N-Butyl-N'-(p-tolylsulfonyl)urea;N-Butyl-N'-p-toluenesulfonylurea;N-n-Butyl-N'-tosylurea;NSC 23813;NSC 87833;Orabet;Oralin;Orezan;Orinase;Orinaz;Oterben;Pramidex;Rastinon;Tolbusal;Tolbutamid;Tolbutamide;Toluina;Tolumid;Tolumide;Toluvan;U 2043;Willbutamide;
EINECS(EC#)200-594-3
Molecular FormulaC₁₂H₁₈N₂O₃S
Molecular Weight270.38

Chemical Properties

Appearancewhite crystalline powder
storage tempRefrigerator

Safety Data

Risk R20/21/22
Safety

Moderately toxic by ingestion and several other routes. A human teratogen. Human reproductive effects by ingestion and possibly other routes: stillbirth, developmental abnormalities of the cardiovascular (circulatory) system and urogenital system, and unspecified neonatal effects. Human systemic effects by ingestion: nausea or vomiting, hypoglycemia. Other experimental teratogenic and reproductive effects. Mutation data reported. Implicated in aplastic anemia. When heated to decomposition it emits very toxic fumes of NO_x and SO_x.
Safety Information about 1-Butyl-3-(4-methylphenyl)sulfonylurea (64-77-7):
Risk Statements about 1-Butyl-3-(4-methylphenyl)sulfonylurea (64-77-7):
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R40: Limited evidence of a carcinogenic effect.
R43: May cause sensitization by skin contact.
Safety Statements about 1-Butyl-3-(4-methylphenyl)sulfonylurea (64-77-7):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 2
RTECS: YS4550000

Toxicity

1.	sce-mus-orl 28,600 µg/kg	MUREAV Mutation Research. 77 (1980),349.
2.	sce-ham-ipr 28,600 µg/kg	MUREAV Mutation Research. 77 (1980),349.
3.	orl-wmn LDLo:1 g/kg:GIT:SYS	ATXKA8 Archiv fuer Toxikologie. 23 (1968),153.
4.	orl-rat LD50:2490 mg/kg	PMDCAY Progress in Medical Chemistry. 1 (1961),187.
5.	ipr-rat LD50:860 mg/kg	FRPSAX Farmaco, Edizione Scientifica. 12 (1957),268.
6.	ivn-rat LD50:700 mg/kg	PMDCAY Progress in Medical Chemistry. 1 (1961),187.
7.	orl-mus LD50:490 mg/kg	IJCREE International Journal of Crude Drug Research. 26 (1988),81.
8.	ipr-mus LD50:650 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 4 (1962),631.
9.	scu-mus LD50:980 mg/kg	NATUAS Nature. 193 (1962),891.
10.	ivn-mus LD50:770 mg/kg	PMDCAY Progress in Medical Chemistry. 1 (1961),187.
11.	ipr-mus LD50:700 mg/kg

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Benzenesulfonamide,N-[(butylamino)carbonyl]-4-methyl- cas no:64-77-7

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