642-78-4|4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)-Products Supply

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)- cas no:642-78-4

Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-,monosodium salt (8CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, [2S-(2a,5a,6b)]-;3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt; Ankerbin;Austrastaph; BRL 1621 sodium salt; Cloxacillin sodium; Cloxacillin sodium salt;Cloxapen; Ekvacillin; Gelstaph; Monosodium cloxacillin; Orbenin; Orbeninsodium; Prevencilina P; Prostaphilin A; Prostaphlin A; Sodium3-(O-chlorophenyl)-5-methyl-4-isoxazolylpenicillin; Sodium cloxacillin; Sodiumorbenin; Sodium syntarpen; Staphybiotic; Syntarpen sodium salt; Tegopen

Identification

Name4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)-
CAS642-78-4
Synonyms4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-,monosodium salt (8CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, [2S-(2a,5a,6b)]-;3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt; Ankerbin;Austrastaph; BRL 1621 sodium salt; Cloxacillin sodium; Cloxacillin sodium salt;Cloxapen; Ekvacillin; Gelstaph; Monosodium cloxacillin; Orbenin; Orbeninsodium; Prevencilina P; Prostaphilin A; Prostaphlin A; Sodium3-(O-chlorophenyl)-5-methyl-4-isoxazolylpenicillin; Sodium cloxacillin; Sodiumorbenin; Sodium syntarpen; Staphybiotic; Syntarpen sodium salt; Tegopen
EINECS(EC#)211-390-9
Molecular FormulaC19H18 Cl N3 O5 S . Na
Molecular Weight457.86315

Chemical Properties

Appearancewhite powder
storage temp2-8°C

Safety Data

Hazard Xn
Risk 36/37/38-42/43
Safety

Safety Information of Cloxacillin sodium (CAS NO.642-78-4):
Hazard Codes: Xn? Harmful
Risk Statements: 36/37/38-42/43
R36/37/38:Irritating to eyes, respiratory system and skin
R42/43:May cause sensitization by inhalation and skin contact
Safety Statements: 26-36-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36:Wear suitable protective clothing
S22:Do not breathe dust
WGK Germany: 2
RTECS: XH8920000
Moderately toxic by intraperitoneal, subcutaneous, intramuscular, and intravenous routes. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of Cl^?, NO_x, SO_x, Na₂O.

Toxicity

1.	???	orl-rat LD50:5?g/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
2.	???	ipr-rat LD50:1350?mg/kg	???	ARZNAD ?? Arzneimittel-Forschung. Drug Research. 15 (1965),322.
3.	???	scu-rat LD50:4200?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
4.	???	ivn-rat LD50:1660?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
5.	???	orl-mus LD50:5?g/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
6.	???	ipr-mus LD50:1170?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
7.	???	scu-mus LD50:1500?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
8.	???	ivn-mus LD50:916?mg/kg	???	FATOAO ?? Farmakologiya i Toksikologiya (Moscow). 31 (1968),232.
9.	???	ims-mus LD50:1220?mg/kg	???	NIIRDN

supplier list

Sichuan Huafamei Enterprise Co., Ltd.: Tel:+86-(28)-8618-1366; Address: Floor Block A,Huaxi Building,5 LinYin Road, Chengdu 610041,

Sol Pharmaceuticals Ltd.: Tel:+91-(40)-2235542; Address: Saphire Building, 5-9-88/2, Fateh Maidan, Hyderabad, Andhra Pradesh 500 001,

Standard Organics Ltd.: Tel:+91-(40)-3237366; Address: 5-9-8812 Saphire bldg., Fateh Maidan, Hyderabad, Andhra Pradesh 500001,

TTK HealthCare Ltd.: Tel:+91-(44)-22368831, 22368872; Address: No. 5, Old Trunk Road, Pallavaram, Chennai, Tamil Nadu 600043,

Taizhou Shengyu Dyestuff Chemical Co.,Ltd.: Tel:+86-(576)-88861016, 88861026; Address: Room 1308-1310, Ocean Plaza, Taizhou, Zhejiang 318000,

Tecoland Corporation: Tel:+1-(732)-603-9577; Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,

Guangzhou Bairui Medicine Co., Ltd.: Tel:+86-(20)-87358016; Address: 2/F,Nan Ya Building A,No.97,South Si You Road, Guangzhou, Guangdong,

Zhejiang Xinhua Pharmaceutical Co Ltd.: Tel:+86-(576)-5588229 5588389; Address: Zhejiang Provincial Chemical and Medical Materials Base Linh, Linhai 317016,

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Wuhan Fortuna Chemical Co., Ltd.: Tel:0086-27-59207850; Address: A2705,Dong Yi Shi Qu,129# XinHua Road

Hebei yanxi chemical co., LTD: Tel:86-311-66561638; Address: Zhang zhe, guangzong county, xingtai city, hebei p

Wuhan Senwayer Century chemical Co.,Ltd: Tel:86-27-59009407; Address: 20#Xudong Street,Wuhan China

Hangzhou Dayangchem Co., Ltd.: Tel:86-571-88938639; Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road

Jinlan Pharm-Drugs Technology Co., Limited: Tel:86-571-85829152; Address: Room 606, Fuyi Center, #298 Quanfuqiao Road, Jiang

HEBEI CUI FENG IMPORT&EXPORT TRADE CO.,LTD: Tel:86-311-80955068; Address: No 98 Gongnong Street,Shijiazhuang Hebei,China

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)- cas no:642-78-4

Directory

supplier list