642-78-4|4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)-Products Supply

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)- cas no:642-78-4

Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-,monosodium salt (8CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, [2S-(2a,5a,6b)]-;3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt; Ankerbin;Austrastaph; BRL 1621 sodium salt; Cloxacillin sodium; Cloxacillin sodium salt;Cloxapen; Ekvacillin; Gelstaph; Monosodium cloxacillin; Orbenin; Orbeninsodium; Prevencilina P; Prostaphilin A; Prostaphlin A; Sodium3-(O-chlorophenyl)-5-methyl-4-isoxazolylpenicillin; Sodium cloxacillin; Sodiumorbenin; Sodium syntarpen; Staphybiotic; Syntarpen sodium salt; Tegopen

Identification

Name4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)-
CAS642-78-4
Synonyms4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-,monosodium salt (8CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, [2S-(2a,5a,6b)]-;3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt; Ankerbin;Austrastaph; BRL 1621 sodium salt; Cloxacillin sodium; Cloxacillin sodium salt;Cloxapen; Ekvacillin; Gelstaph; Monosodium cloxacillin; Orbenin; Orbeninsodium; Prevencilina P; Prostaphilin A; Prostaphlin A; Sodium3-(O-chlorophenyl)-5-methyl-4-isoxazolylpenicillin; Sodium cloxacillin; Sodiumorbenin; Sodium syntarpen; Staphybiotic; Syntarpen sodium salt; Tegopen
EINECS(EC#)211-390-9
Molecular FormulaC19H18 Cl N3 O5 S . Na
Molecular Weight457.86315

Chemical Properties

Appearancewhite powder
storage temp2-8°C

Safety Data

Hazard Xn
Risk 36/37/38-42/43
Safety

Safety Information of Cloxacillin sodium (CAS NO.642-78-4):
Hazard Codes: Xn? Harmful
Risk Statements: 36/37/38-42/43
R36/37/38:Irritating to eyes, respiratory system and skin
R42/43:May cause sensitization by inhalation and skin contact
Safety Statements: 26-36-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36:Wear suitable protective clothing
S22:Do not breathe dust
WGK Germany: 2
RTECS: XH8920000
Moderately toxic by intraperitoneal, subcutaneous, intramuscular, and intravenous routes. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of Cl^?, NO_x, SO_x, Na₂O.

Toxicity

1.	???	orl-rat LD50:5?g/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
2.	???	ipr-rat LD50:1350?mg/kg	???	ARZNAD ?? Arzneimittel-Forschung. Drug Research. 15 (1965),322.
3.	???	scu-rat LD50:4200?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
4.	???	ivn-rat LD50:1660?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
5.	???	orl-mus LD50:5?g/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
6.	???	ipr-mus LD50:1170?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
7.	???	scu-mus LD50:1500?mg/kg	???	NIIRDN ?? “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
8.	???	ivn-mus LD50:916?mg/kg	???	FATOAO ?? Farmakologiya i Toksikologiya (Moscow). 31 (1968),232.
9.	???	ims-mus LD50:1220?mg/kg	???	NIIRDN

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4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt (1:1), (2S,5R,6R)- cas no:642-78-4

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