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Erythromycin stearate cas no:643-22-1

Synonyms: Octadecanoic acid, compd. with erythromycin (1:1);Abboticine;Erythromycin,octadecanoate (salt);Bristamycin (TN);Erypar;Bristamycin;Qidmycin;[(2S,3R,4S,6R)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-3-hydroxy-6-methyl-oxan-4-yl]-dimethyl-azanium; octadecanoate;

Identification
NameErythromycin stearate
CAS643-22-1
SynonymsOctadecanoic acid, compd. with erythromycin (1:1);Abboticine;Erythromycin,octadecanoate (salt);Bristamycin (TN);Erypar;Bristamycin;Qidmycin;[(2S,3R,4S,6R)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-3-hydroxy-6-methyl-oxan-4-yl]-dimethyl-azanium; octadecanoate;
EINECS(EC#)211-396-1
Molecular FormulaC37H67NO13.C18H36O2
Molecular Weight1018.40402
Chemical Properties
Appearancefine white powder
refractive index1.518
storage temp2-8°C
Safety Data

Hazard Xn:Harmful;
Risk R42/43
Safety

Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also ERYTHROMYCIN.
Hazard Codes:? Xn ,Xi
Risk Statements:? 42/43-36/37/38
R42/43: May cause sensitization by inhalation and skin contact
R36/37/38 :?Irritating to eyes, respiratory system and skin
Safety Statements:? 36-26
S26:?? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:?? Wear suitable protective clothing.??
WGK Germany:? 2


HS Code 29415000

Toxicity
1. ???

orl-mus LD50:3112?mg/kg

??? DRUGAY ?? Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews .(ADIS Press Ltd.,Wanchai, Hong Kong.:?)1990,211.
2. ???

ipr-gpg LD50:413?mg/kg

??? DRUGAY ?? Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews .(ADIS Press Ltd.,Wanchai, Hong Kong.:?)1990,211.

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